Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury

Wan Ting Meng; Jing Zhu; Ya Chao Wang; Chang Le Shao; Xiu Ya Li; Ping Ping Lu; Meng Ying Huang; Fang Fang Mou; Hai Dong Guo; Guang Ji

doi:10.1186/s12951-024-02631-0

Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury

Wan Ting Meng, Jing Zhu, Ya Chao Wang, Chang Le Shao, Xiu Ya Li, Ping Ping Lu, Meng Ying Huang, Fang Fang Mou, Hai Dong Guo, Guang Ji

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Original language	English
Article number	382
Journal	Journal of Nanobiotechnology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1186/s12951-024-02631-0
Publication status	Published - Dec 2024
Externally published	Yes

ASJC Scopus Subject Areas

Bioengineering
Medicine (miscellaneous)
Molecular Medicine
Biomedical Engineering
Applied Microbiology and Biotechnology
Pharmaceutical Science

Keywords

Inflammatory factors
microRNA-146a
Milk exosome
Myocardial ischemia-reperfusion injury
NF-κB signaling pathway
Targeting delivery

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10.1186/s12951-024-02631-0

Cite this

Meng, W. T., Zhu, J., Wang, Y. C., Shao, C. L., Li, X. Y., Lu, P. P., Huang, M. Y., Mou, F. F., Guo, H. D., & Ji, G. (2024). Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury. Journal of Nanobiotechnology, 22(1), Article 382. https://doi.org/10.1186/s12951-024-02631-0

Meng, WT, Zhu, J, Wang, YC, Shao, CL, Li, XY, Lu, PP, Huang, MY, Mou, FF, Guo, HD & Ji, G 2024, 'Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury', Journal of Nanobiotechnology, vol. 22, no. 1, 382. https://doi.org/10.1186/s12951-024-02631-0

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AU - Meng, Wan Ting

AU - Zhu, Jing

AU - Wang, Ya Chao

AU - Shao, Chang Le

AU - Li, Xiu Ya

AU - Lu, Ping Ping

AU - Huang, Meng Ying

AU - Mou, Fang Fang

AU - Guo, Hai Dong

AU - Ji, Guang

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/12

Y1 - 2024/12

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KW - microRNA-146a

KW - Milk exosome

KW - Myocardial ischemia-reperfusion injury

KW - NF-κB signaling pathway

KW - Targeting delivery

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Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia-reperfusion injury

ASJC Scopus Subject Areas

Keywords

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