Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe

Biochemistry, Genetics and Molecular Biology

• Eicosanoid Receptor 100%
• Cannabinoid 100%
• Allosteric Site 100%
• Signal Transduction 11%
• Inverse Agonism 11%
• Ligand Binding 5%
• Small Molecule 5%
• Agonist 5%
• G Protein Coupled Receptor 5%
• Allosteric Regulation 5%
• Arrestin 5%
• Internalization 5%
• Cyclic Adenosine Monophosphate 5%
• Isothiocyanate 5%
• Receptor Agonists 5%
• Inverse Agonist 5%
• Somatic Disorder 5%
• Anandamide 5%
• 2-Arachidonoylglycerol 5%

Keyphrases

• Signaling Profile 100%
• Allosteric Probe 5%
• Psychobehavioural 5%
• Focused Library 5%
• Computational Docking 5%
• Functional Profiling 5%
• Neuro-2a 5%
• Probe Dependence 5%
• Receptor Internalization 5%