All trans 1-(3-arylacryloyl)-3,5-bis (pyridin-4-ylmethylene)piperidin-4-ones as curcumin-inspired antineoplastics

Keyphrases

• Trans-1 100%
• Curcumin 100%
• Piperidin-4-one 100%
• Antineoplastic Agents 100%
• Cytotoxicity 50%
• Cancer Cells 50%
• Toxicity Study 50%
• Potent Antioxidant 50%
• IC50 Value 50%
• Methylene 50%
• Anticancer 50%
• Cytostatic 50%
• Cinnamoyl 50%
• 4-Piperidones 50%
• NCI-60 Cell Lines 50%
• 50% Inhibitory Concentration 50%
• Physicochemical Parameters 50%
• Human Fibroblasts 50%
• Representative Test 50%
• Representative Unit Cell 50%
• In Vitro Activity 50%
• Acryloyl 50%
• Topoisomerase II 50%
• QSAR Studies 50%
• Cell Activity 50%

Medicine and Dentistry

• Anticarcinogen 100%
• IC50 100%
• Curcumin 100%
• Cell Line 100%
• In Vitro 50%
• Cytotoxicity 50%
• Cancer Cell 50%
• Antioxidant 50%
• Fibroblast 50%
• Piperidone Derivative 50%
• Cell Activity 50%
• Carbene 50%
• Chemotherapeutic Agent 50%
• Cytostatic Agent 50%
• DNA Topoisomerase (ATP Hydrolysing) 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Anticarcinogen 100%
• IC50 100%
• Curcumin 100%
• Malignant Neoplasm 50%
• Mouse 50%
• Cytotoxicity 50%
• Antioxidant 50%
• DNA Topoisomerase (ATP Hydrolysing) 50%
• Quantitative Structure-Activity Relationship 50%
• Carbene 50%
• Piperidone Derivative 50%
• Cytostatic Agent 50%