All trans 1-(3-arylacryloyl)-3,5-bis (pyridin-4-ylmethylene)piperidin-4-ones as curcumin-inspired antineoplastics

TY - JOUR

T1 - All trans 1-(3-arylacryloyl)-3,5-bis (pyridin-4-ylmethylene)piperidin-4-ones as curcumin-inspired antineoplastics

AU - Paul, Nawal K.

AU - Jha, Mamta

AU - Bhullar, Khushwant S.

AU - Rupasinghe, H. P.Vasantha

AU - Balzarini, Jan

AU - Jha, Amitabh

N1 - Funding Information: The authors thank the following agencies for financial support, namely the Nova Scotia Health Research Foundation (A.J.), Natural Sciences and Engineering Research Council of Canada (A. J.), Fonds voor Wetenschappelijk Onderzoek-Vlaanderen (J. B.). Appreciation is extended to Mrs. Lizette van Berckelaer for conducting the Molt4/C8, CEM and L1210 assays, the National Cancer Institute, U.S.A., which provided the data using the panel of human tumor cell lines and the National Institute of Neurological Disorders and Stroke, U.S.A. for undertaking the short-term toxicity studies in mice. H.P.V.R. gratefully acknowledges funding from the Canada Research Chair program and the Discovery Grant program of the Natural Sciences and Engineering Research Council (NSERC) of Canada. Publisher Copyright: © 2014 Elsevier Masson SAS. All rights reserved.

PY - 2014/11/24

Y1 - 2014/11/24

UR - http://www.scopus.com/inward/record.url?scp=84949116413&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84949116413&partnerID=8YFLogxK

U2 - 10.1016/j.ejmech.2014.09.090

DO - 10.1016/j.ejmech.2014.09.090

M3 - Article

C2 - 25282269

AN - SCOPUS:84949116413

SN - 0223-5234

VL - 87

SP - 461

EP - 470

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

ER -