TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

M. Cole; C. Yap; C. Buckley; W. F. Ng; I. McInnes; A. Filer; S. Siebert; A. Pratt; J. D. Isaacs; D. D. Stocken

doi:10.1186/s13063-021-05384-5

TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

M. Cole, C. Yap, C. Buckley, W. F. Ng, I. McInnes, A. Filer, S. Siebert, A. Pratt, J. D. Isaacs, D. D. Stocken

科研成果: 期刊稿件 › 文章 › 同行评审

源语言	英语
文章编号	433
期刊	Trials
卷	22
期	1
DOI	https://doi.org/10.1186/s13063-021-05384-5
出版状态	已出版 - 12月 2021
已对外发布	是

!!!ASJC Scopus Subject Areas

药学（医学）
医学（杂项）

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10.1186/s13063-021-05384-5

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title = "TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis",

keywords = "Adaptive, CRM, Clinical trial, Dose-finding, Early-phase",

author = "M. Cole and C. Yap and C. Buckley and Ng, {W. F.} and I. McInnes and A. Filer and S. Siebert and A. Pratt and Isaacs, {J. D.} and Stocken, {D. D.}",

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year = "2021",

month = dec,

doi = "10.1186/s13063-021-05384-5",

language = "English",

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T2 - statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

AU - Cole, M.

AU - Yap, C.

AU - Buckley, C.

AU - Ng, W. F.

AU - McInnes, I.

AU - Filer, A.

AU - Siebert, S.

AU - Pratt, A.

AU - Isaacs, J. D.

AU - Stocken, D. D.

PY - 2021/12

Y1 - 2021/12

KW - Adaptive

KW - CRM

KW - Clinical trial

KW - Dose-finding

KW - Early-phase

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UR - http://www.scopus.com/inward/citedby.url?scp=85109388345&partnerID=8YFLogxK

U2 - 10.1186/s13063-021-05384-5

DO - 10.1186/s13063-021-05384-5

M3 - Article

C2 - 34229728

AN - SCOPUS:85109388345

SN - 1745-6215

VL - 22

JO - Trials

JF - Trials

IS - 1

M1 - 433

ER -

TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

!!!ASJC Scopus Subject Areas

联合国可持续发展目标

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