@article{5a32e6e44e0941f4ad721658cb064a3d,
title = "Safety and immunogenicity of a 30-valent M protein-based group a streptococcal vaccine in healthy adult volunteers: A randomized, controlled phase I study",
author = "{\'E}lodie Pastural and McNeil, {Shelly A.} and Donna MacKinnon-Cameron and Lingyun Ye and Langley, {Joanne M.} and Robert Stewart and Martin, {Luis H.} and Hurley, {Gregory J.} and Sanaz Salehi and Penfound, {Thomas A.} and Scott Halperin and Dale, {James B.}",
note = "Funding Information: Financial support was provided by Pan-Provincial Vaccine Enterprise Inc. (PREVENT), Canada and Vaxent, LLC , United States. The sponsors provided the study vaccine and provided some input into the study design. Tissue cross-reactive antibody assays were performed under a contract from the National Institutes of Health , United States (NIAID Contract HHSN272201200003I ), to Dr. Mast at the Blood Research Institute at the Blood Center of Wisconsin. Dr. Dale received funds from the US Public Health Service , United States (NIH grants RO1 AI-010085 and RO1 AI-132117 ). Funding Information: We thank the volunteers who participated in this study; Dr. Alan Mast, Wesley Zwifelhofer and Dr. Susan Maroney at the Blood Research Institute at Blood Center of Wisconsin for the human tissue cross-reactive antibody assays; Dr. Tammy Keough-Ryan (MD, FRCPC, Professor of Medicine, Division of Nephrology, Nova Scotia Health Authority, Dalhousie University) for her assistance with the blinded adjudication of potential renal adverse events; Catherine Brown (study coordinator), Dr. May ElSherif (lab manager) and the nurses at the Canadian Center for Vaccinology for clinical care of volunteers; and Andrea McNeil from ALM Research for monitoring the study. Financial support was provided by Pan-Provincial Vaccine Enterprise Inc. (PREVENT), Canada and Vaxent, LLC, United States. The sponsors provided the study vaccine and provided some input into the study design. Tissue cross-reactive antibody assays were performed under a contract from the National Institutes of Health, United States (NIAID Contract HHSN272201200003I), to Dr. Mast at the Blood Research Institute at the Blood Center of Wisconsin. Dr. Dale received funds from the US Public Health Service, United States (NIH grants RO1 AI-010085 and RO1 AI-132117). Publisher Copyright: {\textcopyright} 2019",
year = "2020",
month = feb,
day = "5",
doi = "10.1016/j.vaccine.2019.12.005",
language = "English",
volume = "38",
pages = "1384--1392",
journal = "Vaccine",
issn = "0264-410X",
publisher = "Elsevier BV",
number = "6",
}
