Reovirus variants with mutations in genome segments S1 and L2 exhibit enhanced virion infectivity and superior oncolysis

Keyphrases

• Virion Infectivity 100%
• Oncolytic Potency 20%
• Immunological Barrier 10%
• Productive Infection 10%
• Equivalent Input 10%
• Virus Assembly 10%
• Viral Protein Synthesis 10%
• Particle Ratios 10%
• Unique mutation 10%
• Syngeneic Mouse Model 10%
• Virus-like Particles 10%
• Viral RNA Synthesis 10%

Immunology and Microbiology

• Protein Synthesis 12%
• RNA Synthesis 12%
• Virus Assembly 12%
• Mammalian Orthoreovirus 2 12%