Potent dialkyl substrate-product analogue inhibitors and inactivators of α-methylacyl-coenzyme A racemase from Mycobacterium tuberculosis by rational design

Mohan Pal; Nicole M. Easton; Hannah Yaphe; Stephen L. Bearne

doi:10.1016/j.bioorg.2018.01.041

Potent dialkyl substrate-product analogue inhibitors and inactivators of α-methylacyl-coenzyme A racemase from Mycobacterium tuberculosis by rational design

Mohan Pal, Nicole M. Easton, Hannah Yaphe, Stephen L. Bearne

Decision Sciences

科研成果: 期刊稿件 › 文章 › 同行评审

9 引用（Scopus）

源语言	英语
页（从-至）	640-650
页数	11
期刊	Bioorganic Chemistry
卷	77
DOI	https://doi.org/10.1016/j.bioorg.2018.01.041
出版状态	已出版 - 4月 2018

!!!ASJC Scopus Subject Areas

生物化学
分子生物学
药物发现
有机化学

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title = "Potent dialkyl substrate-product analogue inhibitors and inactivators of α-methylacyl-coenzyme A racemase from Mycobacterium tuberculosis by rational design",

author = "Mohan Pal and Easton, {Nicole M.} and Hannah Yaphe and Bearne, {Stephen L.}",

note = "Funding Information: This work was supported by a Discovery Grant from the Natural Sciences and Engineering Research Council (NSERC) of Canada ( RGPIN-2016-05083 ) (S.L.B.), an NSERC-USRA (N.M.E.), and a Faye Sobey USRA (N.M.E.). We thank Dr. Mike Lumsden (NMR-3), Dr. Alejandro Cohen, and Greg McCluskey for their assistance in conducting NMR, MS, and DLS experiments, respectively. Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

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AU - Pal, Mohan

AU - Easton, Nicole M.

AU - Yaphe, Hannah

AU - Bearne, Stephen L.

N1 - Funding Information: This work was supported by a Discovery Grant from the Natural Sciences and Engineering Research Council (NSERC) of Canada ( RGPIN-2016-05083 ) (S.L.B.), an NSERC-USRA (N.M.E.), and a Faye Sobey USRA (N.M.E.). We thank Dr. Mike Lumsden (NMR-3), Dr. Alejandro Cohen, and Greg McCluskey for their assistance in conducting NMR, MS, and DLS experiments, respectively. Publisher Copyright: © 2018 Elsevier Inc.

PY - 2018/4

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ER -

Potent dialkyl substrate-product analogue inhibitors and inactivators of α-methylacyl-coenzyme A racemase from Mycobacterium tuberculosis by rational design

!!!ASJC Scopus Subject Areas

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