Mechano-sensitivity of cardiac pacemaker function: Pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity

TY - JOUR

T1 - Mechano-sensitivity of cardiac pacemaker function

T2 - Pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity

AU - Quinn, T. Alexander

AU - Kohl, Peter

N1 - Funding Information: Work of the authors is supported by the Engineering and Physical Science Research Council of the United Kingdom , the British Heart Foundation , the Magdi Yacoub Institute , and the European Commission FP7 Virtual Physiological Human Initiative (Network of Excellence, preDiCT, euHeart) .

PY - 2012/10

Y1 - 2012/10

KW - Beat-by-beat regulation

KW - Calcium-clock

KW - Coupled oscillators

KW - Electrophysiology

KW - Mechano-electric feedback (or coupling)

KW - Membrane-clock

KW - Pacemaker

KW - Rate adaptation

KW - Stretch

UR - http://www.scopus.com/inward/record.url?scp=84868138321&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868138321&partnerID=8YFLogxK

U2 - 10.1016/j.pbiomolbio.2012.08.008

DO - 10.1016/j.pbiomolbio.2012.08.008

M3 - Review article

C2 - 23046620

AN - SCOPUS:84868138321

SN - 0079-6107

VL - 110

SP - 257

EP - 268

JO - Progress in Biophysics and Molecular Biology

JF - Progress in Biophysics and Molecular Biology

IS - 2-3

ER -