Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis

Keyphrases

• Binucleation 16%
• Cdt1 16%
• Cell Cycle Effects 16%
• Cell Microscopy 16%
• Cleavage Furrow 33%
• COP9 Signalosome 66%
• Cullin-RING E3 Ligase 50%
• Deneddylation 16%
• G2 Arrest 16%
• Interphase nucleus 16%
• Kinesin Motor Protein 16%
• Lagging Chromosomes 16%
• Metalloprotease 16%
• Mitotic Cells 33%
• Mitotic Defects 100%
• Mitotic Kinesin 16%
• MKLP1 100%
• MLN4924 83%
• NEDD8 50%
• NEDD8-activating Enzyme 16%
• Neddylation 100%
• Neural Precursor Cell Expressed 16%
• Nuclear Size 16%
• Protein Stability 16%
• Repair Cell 16%
• Ubiquitin-like 16%

Biochemistry, Genetics and Molecular Biology

• Abscission 16%
• Cleavage Furrow 33%
• COP9 Signalosome 66%
• Cullin 50%
• Daughter Cell 16%
• G2 Phase Cell Cycle Checkpoint 16%
• Kinesin 16%
• Mitosis 33%
• NEDD8 66%
• Neddylation 100%
• Nuclear Size 16%