Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity

Dipsikha Biswas; Logan Slade; Luke Duffley; Neil Mueller; Khoi Thien Dao; Angella Mercer; Shanmugasundaram Pakkiriswami; Yassine El Hiani; Petra C. Kienesberger; Thomas Pulinilkunnil

doi:10.1038/s41420-021-00602-0

Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity

Dipsikha Biswas, Logan Slade, Luke Duffley, Neil Mueller, Khoi Thien Dao, Angella Mercer, Shanmugasundaram Pakkiriswami, Yassine El Hiani, Petra C. Kienesberger, Thomas Pulinilkunnil

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21 引用（Scopus）

源语言	英语
文章编号	241
期刊	Cell Death Discovery
卷	7
期	1
DOI	https://doi.org/10.1038/s41420-021-00602-0
出版状态	已出版 - 12月 2021
已对外发布	是

!!!ASJC Scopus Subject Areas

免疫学
细胞和分子神经科学
细胞生物学
癌症研究

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Biswas, D., Slade, L., Duffley, L., Mueller, N., Dao, K. T., Mercer, A., Pakkiriswami, S., El Hiani, Y., Kienesberger, P. C., & Pulinilkunnil, T. (2021). Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity. Cell Death Discovery, 7(1), 文章 241. https://doi.org/10.1038/s41420-021-00602-0

Biswas, D, Slade, L, Duffley, L, Mueller, N, Dao, KT, Mercer, A, Pakkiriswami, S, El Hiani, Y , Kienesberger, PC & Pulinilkunnil, T 2021, 'Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity', Cell Death Discovery, 卷 7, 号码 1, 241. https://doi.org/10.1038/s41420-021-00602-0

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AU - Pakkiriswami, Shanmugasundaram

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Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity

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