Copper-mediated nuclease activity of jadomycin B

TY - JOUR

T1 - Copper-mediated nuclease activity of jadomycin B

AU - Jakeman, David L.

N1 - Funding Information: S.A.M. thanks the Natural Sciences and Engineering Research Council , the Canadian Institutes of Health Research , the Acadia University Faculty of Science , and the Acadia University Department of Chemistry for funding. D.L.J. thanks the Canadian Institutes of Health Research , the Natural Sciences and Engineering Research Council , the Atlantic Chapter of the Canadian Breast Cancer Foundation and the Dalhousie University Pharmacy Endowment fund for funding.

PY - 2011/6/1

Y1 - 2011/6/1

KW - Copper-mediated DNA cleavage

KW - DNA damage

KW - Jadomycins

KW - Reactive oxygen species

UR - http://www.scopus.com/inward/record.url?scp=79957480483&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79957480483&partnerID=8YFLogxK

U2 - 10.1016/j.bmc.2011.04.043

DO - 10.1016/j.bmc.2011.04.043

M3 - Article

C2 - 21565515

AN - SCOPUS:79957480483

SN - 0968-0896

VL - 19

SP - 3357

EP - 3360

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 11

ER -