Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction

Vladimir V. Senatorov; Aaron R. Friedman; Dan Z. Milikovsky; Jonathan Ofer; Rotem Saar-Ashkenazy; Adiel Charbash; Naznin Jahan; Gregory Chin; Eszter Mihaly; Jessica M. Lin; Harrison J. Ramsay; Ariana Moghbel; Marcela K. Preininger; Chelsy R. Eddings; Helen V. Harrison; Rishi Patel; Yizhuo Shen; Hana Ghanim; Huanjie Sheng; Ronel Veksler; Peter H. Sudmant; Albert Becker; Barry Hart; Michael A. Rogawski; Andrew Dillin; Alon Friedman; Daniela Kaufer

doi:10.1126/scitranslmed.aaw8283

Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction

Vladimir V. Senatorov, Aaron R. Friedman, Dan Z. Milikovsky, Jonathan Ofer, Rotem Saar-Ashkenazy, Adiel Charbash, Naznin Jahan, Gregory Chin, Eszter Mihaly, Jessica M. Lin, Harrison J. Ramsay, Ariana Moghbel, Marcela K. Preininger, Chelsy R. Eddings, Helen V. Harrison, Rishi Patel, Yizhuo Shen, Hana Ghanim, Huanjie Sheng, Ronel VekslerPeter H. Sudmant, Albert Becker, Barry Hart, Michael A. Rogawski, Andrew Dillin, Alon Friedman, Daniela Kaufer

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174 引用（Scopus）

源语言	英语
文章编号	eaaw8283
期刊	Science Translational Medicine
卷	11
期	521
DOI	https://doi.org/10.1126/scitranslmed.aaw8283
出版状态	已出版 - 12月 4 2019
已对外发布	是

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Senatorov, V. V., Friedman, A. R., Milikovsky, D. Z., Ofer, J., Saar-Ashkenazy, R., Charbash, A., Jahan, N., Chin, G., Mihaly, E., Lin, J. M., Ramsay, H. J., Moghbel, A., Preininger, M. K., Eddings, C. R., Harrison, H. V., Patel, R., Shen, Y., Ghanim, H., Sheng, H., ... Kaufer, D. (2019). Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction. Science Translational Medicine, 11(521), 文章 eaaw8283. https://doi.org/10.1126/scitranslmed.aaw8283

Senatorov, VV, Friedman, AR, Milikovsky, DZ, Ofer, J, Saar-Ashkenazy, R, Charbash, A, Jahan, N, Chin, G, Mihaly, E, Lin, JM, Ramsay, HJ, Moghbel, A, Preininger, MK, Eddings, CR, Harrison, HV, Patel, R, Shen, Y, Ghanim, H, Sheng, H, Veksler, R, Sudmant, PH, Becker, A, Hart, B, Rogawski, MA, Dillin, A, Friedman, A & Kaufer, D 2019, 'Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction', Science Translational Medicine, 卷 11, 号码 521, eaaw8283. https://doi.org/10.1126/scitranslmed.aaw8283

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AU - Senatorov, Vladimir V.

AU - Friedman, Aaron R.

AU - Milikovsky, Dan Z.

AU - Ofer, Jonathan

AU - Saar-Ashkenazy, Rotem

AU - Charbash, Adiel

AU - Jahan, Naznin

AU - Chin, Gregory

AU - Mihaly, Eszter

AU - Lin, Jessica M.

AU - Ramsay, Harrison J.

AU - Moghbel, Ariana

AU - Preininger, Marcela K.

AU - Eddings, Chelsy R.

AU - Harrison, Helen V.

AU - Patel, Rishi

AU - Shen, Yizhuo

AU - Ghanim, Hana

AU - Sheng, Huanjie

AU - Veksler, Ronel

AU - Sudmant, Peter H.

AU - Becker, Albert

AU - Hart, Barry

AU - Rogawski, Michael A.

AU - Dillin, Andrew

AU - Friedman, Alon

AU - Kaufer, Daniela

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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction

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