The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS)

Alon Kaplan, Hila Zelicha, Anat Yaskolka Meir, Ehud Rinott, Gal Tsaban, Gidon Levakov, Ofer Prager, Moti Salti, Yoram Yovell, Jonathan Ofer, Sebastian Huhn, Frauke Beyer, Veronica Witte, Arno Villringer, Nachshon Meiran, Tamar B. Emesh, Peter Kovacs, Martin Von Bergen, Uta Ceglarek, Matthias BlüherMichael Stumvoll, Frank B. Hu, Meir J. Stampfer, Alon Friedman, Ilan Shelef, Galia Avidan, Iris Shai

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)
Original languageEnglish
Pages (from-to)1270-1281
Number of pages12
JournalAmerican Journal of Clinical Nutrition
Volume115
Issue number5
DOIs
Publication statusPublished - May 1 2022
Externally publishedYes

ASJC Scopus Subject Areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Keywords

  • age-related atrophy
  • aging
  • dietary intervention
  • Green Mediterranean diet
  • hippocampal occupancy score
  • neurodegeneration
  • polyphenols

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Kaplan, A., Zelicha, H., Yaskolka Meir, A., Rinott, E., Tsaban, G., Levakov, G., Prager, O., Salti, M., Yovell, Y., Ofer, J., Huhn, S., Beyer, F., Witte, V., Villringer, A., Meiran, N., Emesh, T. B., Kovacs, P., Von Bergen, M., Ceglarek, U., ... Shai, I. (2022). The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS). American Journal of Clinical Nutrition, 115(5), 1270-1281. https://doi.org/10.1093/ajcn/nqac001