Testing the thrifty gene hypothesis: The Gly482Ser variant in PPARGC1A is associated with BMI in Tongans

Sean Myles; Rod A. Lea; Jun Ohashi; Geoff K. Chambers; Joerg G. Weiss; Emilie Hardouin; Johannes Engelken; Donia P. Macartney-Coxson; David A. Eccles; Izumi Naka; Ryosuke Kimura; Tsukasa Inaoka; Yasuhiro Matsumura; Mark Stoneking

doi:10.1186/1471-2350-12-10

Testing the thrifty gene hypothesis: The Gly482Ser variant in PPARGC1A is associated with BMI in Tongans

Sean Myles, Rod A. Lea, Jun Ohashi, Geoff K. Chambers, Joerg G. Weiss, Emilie Hardouin, Johannes Engelken, Donia P. Macartney-Coxson, David A. Eccles, Izumi Naka, Ryosuke Kimura, Tsukasa Inaoka, Yasuhiro Matsumura, Mark Stoneking

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Original language	English
Article number	10
Journal	BMC Medical Genetics
Volume	12
DOIs	https://doi.org/10.1186/1471-2350-12-10
Publication status	Published - Jan 18 2011
Externally published	Yes

ASJC Scopus Subject Areas

Genetics
Genetics(clinical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/1471-2350-12-10

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Myles, S., Lea, R. A., Ohashi, J., Chambers, G. K., Weiss, J. G., Hardouin, E., Engelken, J., Macartney-Coxson, D. P., Eccles, D. A., Naka, I., Kimura, R., Inaoka, T., Matsumura, Y., & Stoneking, M. (2011). Testing the thrifty gene hypothesis: The Gly482Ser variant in PPARGC1A is associated with BMI in Tongans. BMC Medical Genetics, 12, Article 10. https://doi.org/10.1186/1471-2350-12-10

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title = "Testing the thrifty gene hypothesis: The Gly482Ser variant in PPARGC1A is associated with BMI in Tongans",

author = "Sean Myles and Lea, {Rod A.} and Jun Ohashi and Chambers, {Geoff K.} and Weiss, {Joerg G.} and Emilie Hardouin and Johannes Engelken and Macartney-Coxson, {Donia P.} and Eccles, {David A.} and Izumi Naka and Ryosuke Kimura and Tsukasa Inaoka and Yasuhiro Matsumura and Mark Stoneking",

note = "Funding Information: We are deeply grateful to all participants for their cooperation in providing blood or saliva samples for genotyping. We thank Drs. Viliami Tangi, Ministry of Health, Kingdom of Tonga and Taniela Palu, Diabetes Clinic, Kingdom of Tonga for their understanding and permission to conduct this research; Te Iwi o Rakaipaaka Incorporated and the Ngati Rakaipaaka community of Nuhaka for their participation; Dinusha Bandara, Michael Dannemann and Roger Mundry for statistical advice; and Don Stewart and members of the Department of Biology at Acadia University for use of laboratory facilities. Research supported by the Max Planck Society, ESR Ltd and the United States Department of Agriculture.",

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doi = "10.1186/1471-2350-12-10",

language = "English",

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T1 - Testing the thrifty gene hypothesis

T2 - The Gly482Ser variant in PPARGC1A is associated with BMI in Tongans

AU - Myles, Sean

AU - Lea, Rod A.

AU - Ohashi, Jun

AU - Chambers, Geoff K.

AU - Weiss, Joerg G.

AU - Hardouin, Emilie

AU - Engelken, Johannes

AU - Macartney-Coxson, Donia P.

AU - Eccles, David A.

AU - Naka, Izumi

AU - Kimura, Ryosuke

AU - Inaoka, Tsukasa

AU - Matsumura, Yasuhiro

AU - Stoneking, Mark

N1 - Funding Information: We are deeply grateful to all participants for their cooperation in providing blood or saliva samples for genotyping. We thank Drs. Viliami Tangi, Ministry of Health, Kingdom of Tonga and Taniela Palu, Diabetes Clinic, Kingdom of Tonga for their understanding and permission to conduct this research; Te Iwi o Rakaipaaka Incorporated and the Ngati Rakaipaaka community of Nuhaka for their participation; Dinusha Bandara, Michael Dannemann and Roger Mundry for statistical advice; and Don Stewart and members of the Department of Biology at Acadia University for use of laboratory facilities. Research supported by the Max Planck Society, ESR Ltd and the United States Department of Agriculture.

PY - 2011/1/18

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Testing the thrifty gene hypothesis: The Gly482Ser variant in PPARGC1A is associated with BMI in Tongans

ASJC Scopus Subject Areas

UN SDGs

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