Synergistic Effect of Acarbose-Chlorogenic Acid on α-Glucosidase Inhibition: Kinetics and Interaction Studies Reveal Mixed-Type Inhibition and Denaturant Effect of Chlorogenic Acid

Raliat O. Abioye; O. Charles Nwamba; Ogadimma D. Okagu; Chibuike C. Udenigwe

doi:10.1021/acsfoodscitech.3c00146

Synergistic Effect of Acarbose-Chlorogenic Acid on α-Glucosidase Inhibition: Kinetics and Interaction Studies Reveal Mixed-Type Inhibition and Denaturant Effect of Chlorogenic Acid

Raliat O. Abioye, O. Charles Nwamba, Ogadimma D. Okagu, Chibuike C. Udenigwe

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	ACS Food Science and Technology
DOIs	https://doi.org/10.1021/acsfoodscitech.3c00146
Publication status	Accepted/In press - 2023
Externally published	Yes

ASJC Scopus Subject Areas

Analytical Chemistry
Food Science
Chemistry (miscellaneous)
Organic Chemistry

Keywords

acarbose
biomolecular interactions
chlorogenic acid
enzyme inhibition kinetics
type 2 diabetes
α-glucosidase

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/acsfoodscitech.3c00146

Cite this

@article{6d3dab578514456fa8ec5f88443abd87,

title = "Synergistic Effect of Acarbose-Chlorogenic Acid on α-Glucosidase Inhibition: Kinetics and Interaction Studies Reveal Mixed-Type Inhibition and Denaturant Effect of Chlorogenic Acid",

keywords = "acarbose, biomolecular interactions, chlorogenic acid, enzyme inhibition kinetics, type 2 diabetes, α-glucosidase",

author = "Abioye, {Raliat O.} and Nwamba, {O. Charles} and Okagu, {Ogadimma D.} and Udenigwe, {Chibuike C.}",

note = "Publisher Copyright: {\textcopyright} 2023 American Chemical Society.",

year = "2023",

doi = "10.1021/acsfoodscitech.3c00146",

language = "English",

journal = "ACS Food Science and Technology",

issn = "2692-1944",

publisher = "American Chemical Society",

}

TY - JOUR

T1 - Synergistic Effect of Acarbose-Chlorogenic Acid on α-Glucosidase Inhibition

T2 - Kinetics and Interaction Studies Reveal Mixed-Type Inhibition and Denaturant Effect of Chlorogenic Acid

AU - Abioye, Raliat O.

AU - Nwamba, O. Charles

AU - Okagu, Ogadimma D.

AU - Udenigwe, Chibuike C.

PY - 2023

Y1 - 2023

KW - acarbose

KW - biomolecular interactions

KW - chlorogenic acid

KW - enzyme inhibition kinetics

KW - type 2 diabetes

KW - α-glucosidase

UR - http://www.scopus.com/inward/record.url?scp=85164907645&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85164907645&partnerID=8YFLogxK

U2 - 10.1021/acsfoodscitech.3c00146

DO - 10.1021/acsfoodscitech.3c00146

M3 - Article

AN - SCOPUS:85164907645

SN - 2692-1944

JO - ACS Food Science and Technology

JF - ACS Food Science and Technology

ER -

Synergistic Effect of Acarbose-Chlorogenic Acid on α-Glucosidase Inhibition: Kinetics and Interaction Studies Reveal Mixed-Type Inhibition and Denaturant Effect of Chlorogenic Acid

ASJC Scopus Subject Areas

Keywords

UN SDGs

Access to Document

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