TY - JOUR
T1 - Structure, amphipathy, and topology of the membrane-proximal helix 8 influence apelin receptor plasma membrane localization
AU - Pandey, Aditya
AU - LeBlanc, Danielle M.
AU - Parmar, Hirendrasinh B.
AU - Phạm, Trần Thanh Tâm
AU - Sarker, Muzaddid
AU - Xu, Lingling
AU - Duncan, Roy
AU - Liu, Xiang Qin
AU - Rainey, J. K.
N1 - Funding Information:
Thanks to Bruce Stewart for expert assistance; to Mike Lumsden for 500 MHz NMR spectrometer support (NMR 3 ) and Ian Burton for 700 MHz NMR spectrometer support (NRC); to Xiao Feng at the Dalhousie Chemistry Mass Spectrometry Laboratory; and, to expertise and infrastructure in the Flow Cytometry and Cellular Microscopy and Digital Imaging core facilities (CORES, Dalhousie University, Faculty of Medicine). This work was supported by Canadian Institutes of Health Research (CIHR) Operating Grants ( MOP-111138 to J.K.R.; FDN-143305 to R.D.); a Nova Scotia Health Research Foundation (NSHRF) Scotia Support Grant (to J.K.R. and R.D.); and, Natural Sciences and Engineering Research Council of Canada Discovery Grants ( RGPIN/41823-2015 to X.Q.L., OGP-0183745 to R.D.) A.P. was supported by the Beatrice Hunter Cancer Research Institute with funds provided by the Canadian Imperial Bank of Commerce and the Harvey Graham Cancer Research Fund as part of The Terry Fox Strategic Health Research Training Program in Cancer Research at CIHR; J.K.R. was supported by a CIHR New Investigator Award .
Funding Information:
Thanks to Bruce Stewart for expert assistance; to Mike Lumsden for 500?MHz NMR spectrometer support (NMR3) and Ian Burton for 700?MHz NMR spectrometer support (NRC); to Xiao Feng at the Dalhousie Chemistry Mass Spectrometry Laboratory; and, to expertise and infrastructure in the Flow Cytometry and Cellular Microscopy and Digital Imaging core facilities (CORES, Dalhousie University, Faculty of Medicine). This work was supported by Canadian Institutes of Health Research (CIHR) Operating Grants (MOP-111138 to J.K.R.; FDN-143305 to R.D.); a Nova Scotia Health Research Foundation (NSHRF) Scotia Support Grant (to J.K.R. and R.D.); and, Natural Sciences and Engineering Research Council of Canada Discovery Grants (RGPIN/41823-2015 to X.Q.L. OGP-0183745 to R.D.) A.P. was supported by the Beatrice Hunter Cancer Research Institute with funds provided by the Canadian Imperial Bank of Commerce and the Harvey Graham Cancer Research Fund as part of The Terry Fox Strategic Health Research Training Program in Cancer Research at CIHR; J.K.R. was supported by a CIHR New Investigator Award.
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/11/1
Y1 - 2019/11/1
UR - http://www.scopus.com/inward/record.url?scp=85070523268&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070523268&partnerID=8YFLogxK
U2 - 10.1016/j.bbamem.2019.183036
DO - 10.1016/j.bbamem.2019.183036
M3 - Article
C2 - 31394100
AN - SCOPUS:85070523268
SN - 0005-2736
VL - 1861
JO - Biochimica et Biophysica Acta - Biomembranes
JF - Biochimica et Biophysica Acta - Biomembranes
IS - 11
M1 - 183036
ER -