Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

Rohit Arora; Christian Cao; Mehul Kumar; Sarthak Sinha; Ayan Chanda; Reid McNeil; Divya Samuel; Rahul K. Arora; T. Wayne Matthews; Shamir Chandarana; Robert Hart; Joseph C. Dort; Jeff Biernaskie; Paola Neri; Martin D. Hyrcza; Pinaki Bose

doi:10.1038/s41467-023-40271-4

Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

Rohit Arora, Christian Cao, Mehul Kumar, Sarthak Sinha, Ayan Chanda, Reid McNeil, Divya Samuel, Rahul K. Arora, T. Wayne Matthews, Shamir Chandarana, Robert Hart, Joseph C. Dort, Jeff Biernaskie, Paola Neri, Martin D. Hyrcza, Pinaki Bose

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Original language	English
Article number	5029
Journal	Nature Communications
Volume	14
Issue number	1
DOIs	https://doi.org/10.1038/s41467-023-40271-4
Publication status	Published - Dec 2023
Externally published	Yes

ASJC Scopus Subject Areas

General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Physics and Astronomy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/s41467-023-40271-4

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Arora, R., Cao, C., Kumar, M., Sinha, S., Chanda, A., McNeil, R., Samuel, D., Arora, R. K., Matthews, T. W., Chandarana, S., Hart, R., Dort, J. C., Biernaskie, J., Neri, P., Hyrcza, M. D., & Bose, P. (2023). Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response. Nature Communications, 14(1), Article 5029. https://doi.org/10.1038/s41467-023-40271-4

Arora, R, Cao, C, Kumar, M, Sinha, S, Chanda, A, McNeil, R, Samuel, D, Arora, RK, Matthews, TW, Chandarana, S, Hart, R, Dort, JC, Biernaskie, J, Neri, P, Hyrcza, MD & Bose, P 2023, 'Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response', Nature Communications, vol. 14, no. 1, 5029. https://doi.org/10.1038/s41467-023-40271-4

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title = "Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response",

author = "Rohit Arora and Christian Cao and Mehul Kumar and Sarthak Sinha and Ayan Chanda and Reid McNeil and Divya Samuel and Arora, {Rahul K.} and Matthews, {T. Wayne} and Shamir Chandarana and Robert Hart and Dort, {Joseph C.} and Jeff Biernaskie and Paola Neri and Hyrcza, {Martin D.} and Pinaki Bose",

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AU - Arora, Rohit

AU - Cao, Christian

AU - Kumar, Mehul

AU - Sinha, Sarthak

AU - Chanda, Ayan

AU - McNeil, Reid

AU - Samuel, Divya

AU - Arora, Rahul K.

AU - Matthews, T. Wayne

AU - Chandarana, Shamir

AU - Hart, Robert

AU - Dort, Joseph C.

AU - Biernaskie, Jeff

AU - Neri, Paola

AU - Hyrcza, Martin D.

AU - Bose, Pinaki

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Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

ASJC Scopus Subject Areas

UN SDGs

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University of Calgary Researchers Add New Study Findings to Research in Science (Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response)

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Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

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University of Calgary Researchers Add New Study Findings to Research in Science (Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response)

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