Resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1- phenylethylamine: Chiral discrimination mechanism

Yangfeng Peng, Quan He, Sohrab Rohani, Hilary Jenkins

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)
Original languageEnglish
Pages (from-to)349-355
Number of pages7
JournalChirality
Volume24
Issue number5
DOIs
Publication statusPublished - May 2012
Externally publishedYes

ASJC Scopus Subject Areas

  • Drug Discovery
  • Analytical Chemistry
  • Spectroscopy
  • Catalysis
  • Pharmacology
  • Organic Chemistry

Keywords

  • (R)-(+)-N-benzyl-1-phenylethylamine
  • 2-chloromandelic acid
  • CH/π interaction
  • chiral discrimination
  • chiral recognition
  • crystallization resolution
  • diastereomeric salt
  • hydrogen bond
  • van der Waals

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