@article{912e26683b924bfa94393ca5d2e41559,
title = "Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance",
author = "Colman, {Ruben J.} and Tomoyuki Mizuno and Keizo Fukushima and Haslam, {David B.} and Hyams, {Jeffrey S.} and Brendan Boyle and Noe, {Joshua D.} and D'Haens, {Geert R.} and {Van Limbergen}, Johan and Kelly Chun and Jane Yang and Denson, {Lee A.} and Ollberding, {Nicholas J.} and Vinks, {Alexander A.} and Phillip Minar",
note = "Funding Information: This work was funded in part by the National Institutes of Health (T32 DK 007727 to R.J.C., K23 DK 105229 and R03 DK 118314 to P.M.), the Crohn's and Colitis Foundation to P.M., the Academic Research Committee at Cincinnati Children's Research Foundation to P.M., Microbial Genomics and Metagenomics Laboratory Pilot Award at Cincinnati Children's Hospital Medical Center to P.M. Research Electronic Data Capture (REDCap) electronic data capture tools hosted at Cincinnati Children's Hospital Medical Center were supported in part by the NIH (NIH/NCATS UL1 TR000445). This project was funded in part by the National Institutes of Health grant number P30 DK078392 (clinical component of the Digestive Diseases Research Core Center in Cincinnati). Funding Information: : RJC, TM, KF, DBH, JDN, NJO, LAD, NJO and PM have no personal interests. JSH reported advisory board membership for Janssen, Lilly, Bristol Myers Squibb and consulted for Takeda, Boehringer Ingelheim, Thetis Pharmaceuticals. BB owns patent 9,549,761 related to endoscopic foreign body retrieval device. Device is unrelated to the content of this manuscript. GRD has served as an consultant for Abbvie, Agomab, AstraZeneca, AM Pharma, AMT, Arena Pharmaceuticals, Bristol Meiers Squibb, Boehringer Ingelheim, Celltrion, Eli Lilly, Exeliom Biosciences, Exo Biologics, Galapagos, Index Pharmaceuticals, Kaleido, Roche, Gilead, Glaxo Smith Kline, Gossamerbio, Pfizer, Immunic, Johnson and Johnson, Origo, Polpharma, Procise Diagnostics, Prometheus laboratories, Prometheus Biosciences, Progenity, Protagonist. GRD has served as a speaker for Abbvie, Arena, Galapagos, Gilead, Pfizer, BMS, Takeda. JVL has served as a speaker for Nestle Health Science, Pfizer and Nutricia/Danone. JVL has received research funding from Nestle Health Science. KC and JY are employees of Labcorp. JY owns stocks and shares in Labcorp. AAV has received research funding from the Gerber foundation, not related to the content of this manuscript. Declarations of personal interests Publisher Copyright: {\textcopyright} 2022 The Authors. Alimentary Pharmacology & Therapeutics published by John Wiley & Sons Ltd.",
year = "2023",
month = mar,
doi = "10.1111/apt.17277",
language = "English",
volume = "57",
pages = "524--539",
journal = "Alimentary Pharmacology and Therapeutics",
issn = "0269-2813",
publisher = "Wiley-Blackwell",
number = "5",
}