Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells

Keyphrases

• Carbocyclic 100%
• Top2 100%
• Polo-like Kinase 1 (PLK1) 100%
• Pathway Signaling 50%
• Epidermal Growth Receptor 50%
• Cyclin-dependent Kinase 2 (CDK2) 50%
• Growth Hormone Receptor 50%
• PLK3 50%
• Topoisomerase 50%
• PLK2 50%
• HTERT Gene 50%
• Activating Transcription Factor 2 (ATF2) 50%
• Human Hepatocellular Carcinoma Cell Line 50%
• MDM2 Gene 50%
• Lung Cells 50%
• Murine Double Minute 4 (MDM4) 50%
• Immunoadjuvant 50%
• AKT2 50%
• Drug Resistance Gene 50%
• Immortality 50%
• Apoptotic Caspases 50%
• Cyclin-dependent Kinase 9 (CDK9) 50%
• Insulin-like Growth Factor 1 Receptor (IGF1R) 50%
• BIRC5 50%
• ErbB3 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Aurora Kinase 100%
• Polo Like Kinase 1 50%
• Cathepsin 50%
• Immunologic Adjuvant 50%

Biochemistry, Genetics and Molecular Biology

• Aurora Kinase 40%
• KRAS 20%
• HRAS 20%
• MDM4 20%
• PLK1 20%
• Refined Hydrothermolytic Oxidation Acid 20%
• Topoisomerase 20%
• ERBB3 20%
• Polo-Like Kinase 20%