Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial

Arif Manji; Yvan Samson; Rebecca J. Deyell; Donna L. Johnston; Victor A. Lewis; Alexandra P. Zorzi; Jason N. Berman; Kathy Brodeur-Robb; Ellen Morrison; Lynn Kee; Sushil Kumar; Sylvain Baruchel; James A. Whitlock; Daniel A. Morgenstern

doi:10.3390/cancers14122985

Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial

Arif Manji, Yvan Samson, Rebecca J. Deyell, Donna L. Johnston, Victor A. Lewis, Alexandra P. Zorzi, Jason N. Berman, Kathy Brodeur-Robb, Ellen Morrison, Lynn Kee, Sushil Kumar, Sylvain Baruchel, James A. Whitlock, Daniel A. Morgenstern

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Original language	English
Article number	2985
Journal	Cancers
Volume	14
Issue number	12
DOIs	https://doi.org/10.3390/cancers14122985
Publication status	Published - Jun 1 2022
Externally published	Yes

ASJC Scopus Subject Areas

Oncology
Cancer Research

Keywords

angiogenesis
children
metronomic
pazopanib
pediatric
phase I trial
topotecan

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/cancers14122985

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Manji, A., Samson, Y., Deyell, R. J., Johnston, D. L., Lewis, V. A., Zorzi, A. P., Berman, J. N., Brodeur-Robb, K., Morrison, E., Kee, L., Kumar, S., Baruchel, S., Whitlock, J. A., & Morgenstern, D. A. (2022). Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial. Cancers, 14(12), Article 2985. https://doi.org/10.3390/cancers14122985

Manji, A, Samson, Y, Deyell, RJ, Johnston, DL, Lewis, VA, Zorzi, AP, Berman, JN, Brodeur-Robb, K, Morrison, E, Kee, L, Kumar, S, Baruchel, S, Whitlock, JA & Morgenstern, DA 2022, 'Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial', Cancers, vol. 14, no. 12, 2985. https://doi.org/10.3390/cancers14122985

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keywords = "angiogenesis, children, metronomic, pazopanib, pediatric, phase I trial, topotecan",

author = "Arif Manji and Yvan Samson and Deyell, {Rebecca J.} and Johnston, {Donna L.} and Lewis, {Victor A.} and Zorzi, {Alexandra P.} and Berman, {Jason N.} and Kathy Brodeur-Robb and Ellen Morrison and Lynn Kee and Sushil Kumar and Sylvain Baruchel and Whitlock, {James A.} and Morgenstern, {Daniel A.}",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

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doi = "10.3390/cancers14122985",

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T1 - Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors

T2 - A C17 Canadian Phase I Clinical Trial

AU - Manji, Arif

AU - Samson, Yvan

AU - Deyell, Rebecca J.

AU - Johnston, Donna L.

AU - Lewis, Victor A.

AU - Zorzi, Alexandra P.

AU - Berman, Jason N.

AU - Brodeur-Robb, Kathy

AU - Morrison, Ellen

AU - Kee, Lynn

AU - Kumar, Sushil

AU - Baruchel, Sylvain

AU - Whitlock, James A.

AU - Morgenstern, Daniel A.

PY - 2022/6/1

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KW - children

KW - metronomic

KW - pazopanib

KW - pediatric

KW - phase I trial

KW - topotecan

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Low-Dose Metronomic Topotecan and Pazopanib (TOPAZ) in Children with Relapsed or Refractory Solid Tumors: A C17 Canadian Phase I Clinical Trial

ASJC Scopus Subject Areas

Keywords

UN SDGs

Access to Document

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