@article{810d694a06104ed1baedf2bf60b8f758,
title = "High-Sensitivity Cardiac Troponin—Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women (CODE-MI): Rationale and design for a multicenter, stepped-wedge, cluster-randomized trial",
author = "Yinshan Zhao and Mona Izadnegahdar and Lee, {May K.} and Kavsak, {Peter A.} and Joel Singer and Frank Scheuermeyer and Udell, {Jacob A.} and Simon Robinson and Norris, {Colleen M.} and Lyon, {Andrew W.} and Louise Pilote and Jafna Cox and Ansar Hassan and Anni Rychtera and Denise Johnson and Mills, {Nicholas L.} and Jim Christenson and Humphries, {Karin H.}",
note = "Funding Information: We thank all participating hospitals; investigators; physicians; our patient partners; the CODE-MI Steering, Data Monitoring, and Education Committee members; and Salima Jutha, the national coordinator. Without their support and engagement, this study would not be possible. N. L. M. is supported by the Butler Senior Clinical Research Fellowship from the British Heart Foundation ( FS/16/14/32023 ). Funding Information: CODE-MI is funded by: the Canadian Institutes for Health Research and in-kind contribution and unencumbered educational support for knowledge translation activities from Roche Diagnostics International, Ltd, and Beckman Coulter, Inc. Funding Information: This trial is funded by the Canadian Institutes of Health Research. The funding source had no role in the design, trial conduct, analysis, or decision to publish the results. The hs-cTn manufacturers, Beckman-Coulter, Roche, and Siemens, contributed assay kits for the participating hospitals and funds to support knowledge translation. However, none of the manufacturers had any involvement in the study design, analytic plan, or knowledge translation.We thank all participating hospitals; investigators; physicians; our patient partners; the CODE-MI Steering, Data Monitoring, and Education Committee members; and Salima Jutha, the national coordinator. Without their support and engagement, this study would not be possible. N. L. M. is supported by the Butler Senior Clinical Research Fellowship from the British Heart Foundation (FS/16/14/32023). CODE-MI is funded by: the Canadian Institutes for Health Research and in-kind contribution and unencumbered educational support for knowledge translation activities from Roche Diagnostics International, Ltd, and Beckman Coulter, Inc. P. K. has received grants/reagents/consultant/advisor/ honoraria from Abbott Laboratories, Abbott Point of Care, Abbott Diagnostics Division Canada, Beckman Coulter, Ortho Clinical Diagnostics, Randox Laboratories, Roche Diagnostics, and Siemens Healthcare Diagnostics and is listed as an inventor in patents in the acute cardiovascular biomarker field filed by McMaster University. N. L. M. reports research grants from Siemens Healthineers and Abbott Diagnostics to the University of Edinburgh and honoraria from Siemens Healthineers, Abbot Diagnostics, and Roche Diagnostics. J.A.U. is supported by a Heart and Stroke Foundation National New Investigator-Ontario Clinician Scientist Award and an Ontario Ministry of Research Innovation and Science Early Researcher Award, received personal fees for consulting for or honoraria from Amgen, AstraZeneca, Boehringer-Ingelheim, Janssen, Merck, Novartis and Sanofi and reports grant support to his institutions from AstraZeneca, Novartis and Sanofi. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = nov,
doi = "10.1016/j.ahj.2020.06.013",
language = "English",
volume = "229",
pages = "18--28",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
}