Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

Lee A. Denson; Ingrid Jurickova; Rebekah Karns; Kelly A. Shaw; David J. Cutler; David Okou; C. Alexander Valencia; Anne Dodd; Kajari Mondal; Bruce J. Aronow; Yael Haberman; Aaron Linn; Adam Price; Ramona Bezold; Kathleen Lake; Kimberly Jackson; Thomas D. Walters; Anne Griffiths; Robert N. Baldassano; Joshua D. Noe; Jeffrey S. Hyams; Wallace V. Crandall; Barbara S. Kirschner; Melvin B. Heyman; Scott Snapper; Stephen L. Guthery; Marla C. Dubinsky; Neal S. Leleiko; Anthony R. Otley; Ramnik J. Xavier; Christine Stevens; Mark J. Daly; Michael E. Zwick; Subra Kugathasan

doi:10.1093/ibd/izy265

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

Lee A. Denson, Ingrid Jurickova, Rebekah Karns, Kelly A. Shaw, David J. Cutler, David Okou, C. Alexander Valencia, Anne Dodd, Kajari Mondal, Bruce J. Aronow, Yael Haberman, Aaron Linn, Adam Price, Ramona Bezold, Kathleen Lake, Kimberly Jackson, Thomas D. Walters, Anne Griffiths, Robert N. Baldassano, Joshua D. NoeJeffrey S. Hyams, Wallace V. Crandall, Barbara S. Kirschner, Melvin B. Heyman, Scott Snapper, Stephen L. Guthery, Marla C. Dubinsky, Neal S. Leleiko, Anthony R. Otley, Ramnik J. Xavier, Christine Stevens, Mark J. Daly, Michael E. Zwick, Subra Kugathasan

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Original language	English
Pages (from-to)	547-560
Number of pages	14
Journal	Inflammatory Bowel Diseases
Volume	25
Issue number	3
DOIs	https://doi.org/10.1093/ibd/izy265
Publication status	Published - Feb 21 2019
Externally published	Yes

ASJC Scopus Subject Areas

Gastroenterology
Immunology and Allergy

Keywords

GM-CSF
RNA sequencing
STAT5
neutrophil
pediatric inflammatory bowel disease
whole-exome sequencing

Access to Document

10.1093/ibd/izy265

Cite this

Denson, L. A., Jurickova, I., Karns, R., Shaw, K. A., Cutler, D. J., Okou, D., Alexander Valencia, C., Dodd, A., Mondal, K., Aronow, B. J., Haberman, Y., Linn, A., Price, A., Bezold, R., Lake, K., Jackson, K., Walters, T. D., Griffiths, A., Baldassano, R. N., ... Kugathasan, S. (2019). Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory Bowel Diseases, 25(3), 547-560. https://doi.org/10.1093/ibd/izy265

Denson, LA, Jurickova, I, Karns, R, Shaw, KA, Cutler, DJ, Okou, D, Alexander Valencia, C, Dodd, A, Mondal, K, Aronow, BJ, Haberman, Y, Linn, A, Price, A, Bezold, R, Lake, K, Jackson, K, Walters, TD, Griffiths, A, Baldassano, RN, Noe, JD, Hyams, JS, Crandall, WV, Kirschner, BS, Heyman, MB, Snapper, S, Guthery, SL, Dubinsky, MC, Leleiko, NS, Otley, AR, Xavier, RJ, Stevens, C, Daly, MJ, Zwick, ME & Kugathasan, S 2019, 'Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease', Inflammatory Bowel Diseases, vol. 25, no. 3, pp. 547-560. https://doi.org/10.1093/ibd/izy265

@article{8bb2b706dfeb4cfaac97ce32d8305587,

title = "Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease",

keywords = "GM-CSF, RNA sequencing, STAT5, neutrophil, pediatric inflammatory bowel disease, whole-exome sequencing",

author = "Denson, {Lee A.} and Ingrid Jurickova and Rebekah Karns and Shaw, {Kelly A.} and Cutler, {David J.} and David Okou and {Alexander Valencia}, C. and Anne Dodd and Kajari Mondal and Aronow, {Bruce J.} and Yael Haberman and Aaron Linn and Adam Price and Ramona Bezold and Kathleen Lake and Kimberly Jackson and Walters, {Thomas D.} and Anne Griffiths and Baldassano, {Robert N.} and Noe, {Joshua D.} and Hyams, {Jeffrey S.} and Crandall, {Wallace V.} and Kirschner, {Barbara S.} and Heyman, {Melvin B.} and Scott Snapper and Guthery, {Stephen L.} and Dubinsky, {Marla C.} and Leleiko, {Neal S.} and Otley, {Anthony R.} and Xavier, {Ramnik J.} and Christine Stevens and Daly, {Mark J.} and Zwick, {Michael E.} and Subra Kugathasan",

year = "2019",

month = feb,

day = "21",

doi = "10.1093/ibd/izy265",

language = "English",

volume = "25",

pages = "547--560",

journal = "Inflammatory Bowel Diseases",

issn = "1078-0998",

publisher = "John Wiley and Sons Inc.",

number = "3",

}

TY - JOUR

T1 - Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

AU - Denson, Lee A.

AU - Jurickova, Ingrid

AU - Karns, Rebekah

AU - Shaw, Kelly A.

AU - Cutler, David J.

AU - Okou, David

AU - Alexander Valencia, C.

AU - Dodd, Anne

AU - Mondal, Kajari

AU - Aronow, Bruce J.

AU - Haberman, Yael

AU - Linn, Aaron

AU - Price, Adam

AU - Bezold, Ramona

AU - Lake, Kathleen

AU - Jackson, Kimberly

AU - Walters, Thomas D.

AU - Griffiths, Anne

AU - Baldassano, Robert N.

AU - Noe, Joshua D.

AU - Hyams, Jeffrey S.

AU - Crandall, Wallace V.

AU - Kirschner, Barbara S.

AU - Heyman, Melvin B.

AU - Snapper, Scott

AU - Guthery, Stephen L.

AU - Dubinsky, Marla C.

AU - Leleiko, Neal S.

AU - Otley, Anthony R.

AU - Xavier, Ramnik J.

AU - Stevens, Christine

AU - Daly, Mark J.

AU - Zwick, Michael E.

AU - Kugathasan, Subra

PY - 2019/2/21

Y1 - 2019/2/21

KW - GM-CSF

KW - RNA sequencing

KW - STAT5

KW - neutrophil

KW - pediatric inflammatory bowel disease

KW - whole-exome sequencing

UR - http://www.scopus.com/inward/record.url?scp=85061961459&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85061961459&partnerID=8YFLogxK

U2 - 10.1093/ibd/izy265

DO - 10.1093/ibd/izy265

M3 - Article

C2 - 30124884

AN - SCOPUS:85061961459

SN - 1078-0998

VL - 25

SP - 547

EP - 560

JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

IS - 3

ER -

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

ASJC Scopus Subject Areas

Keywords

Access to Document

Other files and links

Fingerprint

Cite this