@article{04fa79125c4e49608d94fdb03ba9c8d9,
title = "Effect of high-dose vitamin D supplementation on radiographically detectable bone disease of very low birth weight infants",
author = "Evans, {Jacquelyn R.} and Allen, {Alexander C.} and Stinson, {Dora A.} and Hamilton, {David C.} and {John Brown}, {B. St} and Vincer, {Michael J.} and Raad, {May A.} and Gundberg, {Caren M.} and Cole, {David E.C.}",
note = "Funding Information: Radiographic evidence of bone disease, encompassing the spectrum from mild hypomineralization to frank rickets, commonly occurs in very low birth weight infants. Although most patients will eventually recover spontaneously, pre- Supported by a Medical Research of Canada grant to Dr. David Cole. Submitted for publication March 22, 1988; accepted July 14, 1989. Reprint requests: Jacquelyn R. Evans, MD, Department of Neonatal Paediatrics, Grace Maternity Hospital, 5821 University Ave., Halifax, Nova Scotia B3H 1W3, Canada. 9/23/15253 vention of bone disease in the VLBW infant is indicated because of the increased risk of fractures, 1 late-onset respiratory distress resulting from rachitic softening of the chest wall,Z, 3 and reduced short-term linear growth. 35 The cause of bone disease in the VLBW infant is multifactorial; vitamin D deficiency has been implicated as one important factor. Prematurely born infants are especially prone to disturbances in vitamin D metabolism. Rosen et al. 6 demonstrated that they are slow to correct low plasma 25-hydroxyvitamin D levels; Hillman and Haddad 7 showed that even when fed fortified formulas, preterm infants fail to achieve satisfactory plasma 25-(OH)D concentrations",
year = "1989",
month = nov,
doi = "10.1016/S0022-3476(89)80662-6",
language = "English",
volume = "115",
pages = "779--786",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "5 PART 1",
}