Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells

Mia Levite; Daniel Zelig; Alon Friedman; Nili Ilouz; Raya Eilam; Zohar Bromberg; Ally Ahmed Ramadhan Lasu; Sagit Arbel-Alon; Shimon Edvardson; Mark Tarshish; Lul P. Riek; Richard Lino Lako; Benjamin Reubinoff; Mario Lebendiker; Dayana Yaish; Alexandra Stavsky; Eithan Galun

doi:10.1016/j.jaut.2020.102462

Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells

Mia Levite, Daniel Zelig, Alon Friedman, Nili Ilouz, Raya Eilam, Zohar Bromberg, Ally Ahmed Ramadhan Lasu, Sagit Arbel-Alon, Shimon Edvardson, Mark Tarshish, Lul P. Riek, Richard Lino Lako, Benjamin Reubinoff, Mario Lebendiker, Dayana Yaish, Alexandra Stavsky, Eithan Galun

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Original language	English
Article number	102462
Journal	Journal of Autoimmunity
Volume	112
DOIs	https://doi.org/10.1016/j.jaut.2020.102462
Publication status	Published - Aug 2020
Externally published	Yes

ASJC Scopus Subject Areas

Immunology and Allergy
Immunology

Keywords

AMPA receptors
Autoimmune diseases
Autoimmune epilepsy
Dual-targeted autoimmune sword
Epilepsy
GluR3 antibodies
GluR3B peptide
GluR3B peptide antibodies
Glutamate receptor antibodies
NMDA receptors
Nodding syndrome
Onchocerciasis Associated Epilepsy (OAE)
T cells

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Levite, M., Zelig, D., Friedman, A., Ilouz, N., Eilam, R., Bromberg, Z., Ramadhan Lasu, A. A., Arbel-Alon, S., Edvardson, S., Tarshish, M., Riek, L. P., Lako, R. L., Reubinoff, B., Lebendiker, M., Yaish, D., Stavsky, A., & Galun, E. (2020). Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells. Journal of Autoimmunity, 112, Article 102462. https://doi.org/10.1016/j.jaut.2020.102462

Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells. / Levite, Mia; Zelig, Daniel; Friedman, Alon et al.
In: Journal of Autoimmunity, Vol. 112, 102462, 08.2020.

Research output: Contribution to journal › Article › peer-review

Levite, M, Zelig, D, Friedman, A, Ilouz, N, Eilam, R, Bromberg, Z, Ramadhan Lasu, AA, Arbel-Alon, S, Edvardson, S, Tarshish, M, Riek, LP, Lako, RL, Reubinoff, B, Lebendiker, M, Yaish, D, Stavsky, A & Galun, E 2020, 'Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells', Journal of Autoimmunity, vol. 112, 102462. https://doi.org/10.1016/j.jaut.2020.102462

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title = "Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells",

keywords = "AMPA receptors, Autoimmune diseases, Autoimmune epilepsy, Dual-targeted autoimmune sword, Epilepsy, GluR3 antibodies, GluR3B peptide, GluR3B peptide antibodies, Glutamate receptor antibodies, NMDA receptors, Nodding syndrome, Onchocerciasis Associated Epilepsy (OAE), T cells",

author = "Mia Levite and Daniel Zelig and Alon Friedman and Nili Ilouz and Raya Eilam and Zohar Bromberg and {Ramadhan Lasu}, {Ally Ahmed} and Sagit Arbel-Alon and Shimon Edvardson and Mark Tarshish and Riek, {Lul P.} and Lako, {Richard Lino} and Benjamin Reubinoff and Mario Lebendiker and Dayana Yaish and Alexandra Stavsky and Eithan Galun",

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year = "2020",

month = aug,

doi = "10.1016/j.jaut.2020.102462",

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AU - Levite, Mia

AU - Zelig, Daniel

AU - Friedman, Alon

AU - Ilouz, Nili

AU - Eilam, Raya

AU - Bromberg, Zohar

AU - Ramadhan Lasu, Ally Ahmed

AU - Arbel-Alon, Sagit

AU - Edvardson, Shimon

AU - Tarshish, Mark

AU - Riek, Lul P.

AU - Lako, Richard Lino

AU - Reubinoff, Benjamin

AU - Lebendiker, Mario

AU - Yaish, Dayana

AU - Stavsky, Alexandra

AU - Galun, Eithan

PY - 2020/8

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KW - Autoimmune diseases

KW - Autoimmune epilepsy

KW - Dual-targeted autoimmune sword

KW - Epilepsy

KW - GluR3 antibodies

KW - GluR3B peptide

KW - GluR3B peptide antibodies

KW - Glutamate receptor antibodies

KW - NMDA receptors

KW - Nodding syndrome

KW - Onchocerciasis Associated Epilepsy (OAE)

KW - T cells

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Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells

ASJC Scopus Subject Areas

Keywords

UN SDGs

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