Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome

Jeffrey Ng; Simon A. Hirota; Olaf Gross; Yan Li; Annegret Ulke-Lemee; Mireille S. Potentier; L. Patrick Schenck; Akosua Vilaysane; Mark E. Seamone; Hanping Feng; Glen D. Armstrong; Jurg Tschopp; Justin A. MacDonald; Daniel A. Muruve; Paul L. Beck

doi:10.1053/j.gastro.2010.04.005

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome

Jeffrey Ng, Simon A. Hirota, Olaf Gross, Yan Li, Annegret Ulke-Lemee, Mireille S. Potentier, L. Patrick Schenck, Akosua Vilaysane, Mark E. Seamone, Hanping Feng, Glen D. Armstrong, Jurg Tschopp, Justin A. MacDonald, Daniel A. Muruve, Paul L. Beck

Research output: Contribution to journal › Article › peer-review

191 Citations (Scopus)

Original language	English
Pages (from-to)	542-552.e1-e3
Journal	Gastroenterology
Volume	139
Issue number	2
DOIs	https://doi.org/10.1053/j.gastro.2010.04.005
Publication status	Published - 2010
Externally published	Yes

ASJC Scopus Subject Areas

Hepatology
Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1053/j.gastro.2010.04.005

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Ng, J., Hirota, S. A., Gross, O., Li, Y., Ulke-Lemee, A., Potentier, M. S., Schenck, L. P., Vilaysane, A., Seamone, M. E., Feng, H., Armstrong, G. D., Tschopp, J., MacDonald, J. A., Muruve, D. A., & Beck, P. L. (2010). Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology, 139(2), 542-552.e1-e3. https://doi.org/10.1053/j.gastro.2010.04.005

Ng, J, Hirota, SA, Gross, O, Li, Y, Ulke-Lemee, A, Potentier, MS, Schenck, LP, Vilaysane, A, Seamone, ME, Feng, H, Armstrong, GD, Tschopp, J, MacDonald, JA, Muruve, DA & Beck, PL 2010, 'Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome', Gastroenterology, vol. 139, no. 2, pp. 542-552.e1-e3. https://doi.org/10.1053/j.gastro.2010.04.005

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title = "Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome",

author = "Jeffrey Ng and Hirota, {Simon A.} and Olaf Gross and Yan Li and Annegret Ulke-Lemee and Potentier, {Mireille S.} and Schenck, {L. Patrick} and Akosua Vilaysane and Seamone, {Mark E.} and Hanping Feng and Armstrong, {Glen D.} and Jurg Tschopp and MacDonald, {Justin A.} and Muruve, {Daniel A.} and Beck, {Paul L.}",

note = "Funding Information: Funding Supported by operating grants from the Canadian Institutes for Health Research and infrastructure grants from the Canadian Foundation for Innovation . D.A.M. and J.A.M. hold Tier II Canada Research Chairs. J.A.M., D.A.M., and P.L.B. are recipients of Alberta Heritage Foundation for Medical Research Scholar Awards. S.A.H. was supported by a Canadian Association of Gastroenterology/Canadian Institutes of Health Research/Alberta Heritage Foundation for Medical Research postdoctoral fellowship. ",

year = "2010",

doi = "10.1053/j.gastro.2010.04.005",

language = "English",

volume = "139",

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T1 - Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome

AU - Ng, Jeffrey

AU - Hirota, Simon A.

AU - Gross, Olaf

AU - Li, Yan

AU - Ulke-Lemee, Annegret

AU - Potentier, Mireille S.

AU - Schenck, L. Patrick

AU - Vilaysane, Akosua

AU - Seamone, Mark E.

AU - Feng, Hanping

AU - Armstrong, Glen D.

AU - Tschopp, Jurg

AU - MacDonald, Justin A.

AU - Muruve, Daniel A.

AU - Beck, Paul L.

N1 - Funding Information: Funding Supported by operating grants from the Canadian Institutes for Health Research and infrastructure grants from the Canadian Foundation for Innovation . D.A.M. and J.A.M. hold Tier II Canada Research Chairs. J.A.M., D.A.M., and P.L.B. are recipients of Alberta Heritage Foundation for Medical Research Scholar Awards. S.A.H. was supported by a Canadian Association of Gastroenterology/Canadian Institutes of Health Research/Alberta Heritage Foundation for Medical Research postdoctoral fellowship.

PY - 2010

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SN - 0016-5085

VL - 139

SP - 542-552.e1-e3

JO - Gastroenterology

JF - Gastroenterology

IS - 2

ER -

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome

ASJC Scopus Subject Areas

UN SDGs

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