Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

Kenneth D'Souza; Carine Nzirorera; Andrew M. Cowie; Geena P. Varghese; Purvi Trivedi; Thomas O. Eichmann; Dipsikha Biswas; Mohamed Touaibia; Andrew J. Morris; Vassilis Aidinis; Daniel A. Kane; Thomas Pulinilkunnil; Petra C. Kienesberger

doi:10.1194/jlr.M082008

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

Kenneth D'Souza, Carine Nzirorera, Andrew M. Cowie, Geena P. Varghese, Purvi Trivedi, Thomas O. Eichmann, Dipsikha Biswas, Mohamed Touaibia, Andrew J. Morris, Vassilis Aidinis, Daniel A. Kane, Thomas Pulinilkunnil, Petra C. Kienesberger

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Original language	English
Pages (from-to)	1805-1817
Number of pages	13
Journal	Journal of Lipid Research
Volume	59
Issue number	10
DOIs	https://doi.org/10.1194/jlr.M082008
Publication status	Published - 2018
Externally published	Yes

ASJC Scopus Subject Areas

Endocrinology
Biochemistry
Cell Biology

Keywords

Diet effects/lipid metabolism
Glucose
Pyruvate
Respiration
Skeletal muscle

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1194/jlr.M082008

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D'Souza, K., Nzirorera, C., Cowie, A. M., Varghese, G. P., Trivedi, P., Eichmann, T. O., Biswas, D., Touaibia, M., Morris, A. J., Aidinis, V., Kane, D. A., Pulinilkunnil, T., & Kienesberger, P. C. (2018). Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. Journal of Lipid Research, 59(10), 1805-1817. https://doi.org/10.1194/jlr.M082008

D'Souza, K, Nzirorera, C, Cowie, AM, Varghese, GP, Trivedi, P, Eichmann, TO, Biswas, D, Touaibia, M, Morris, AJ, Aidinis, V, Kane, DA, Pulinilkunnil, T & Kienesberger, PC 2018, 'Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism', Journal of Lipid Research, vol. 59, no. 10, pp. 1805-1817. https://doi.org/10.1194/jlr.M082008

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title = "Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism",

keywords = "Diet effects/lipid metabolism, Glucose, Pyruvate, Respiration, Skeletal muscle",

author = "Kenneth D'Souza and Carine Nzirorera and Cowie, {Andrew M.} and Varghese, {Geena P.} and Purvi Trivedi and Eichmann, {Thomas O.} and Dipsikha Biswas and Mohamed Touaibia and Morris, {Andrew J.} and Vassilis Aidinis and Kane, {Daniel A.} and Thomas Pulinilkunnil and Kienesberger, {Petra C.}",

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doi = "10.1194/jlr.M082008",

language = "English",

volume = "59",

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T1 - Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

AU - D'Souza, Kenneth

AU - Nzirorera, Carine

AU - Cowie, Andrew M.

AU - Varghese, Geena P.

AU - Trivedi, Purvi

AU - Eichmann, Thomas O.

AU - Biswas, Dipsikha

AU - Touaibia, Mohamed

AU - Morris, Andrew J.

AU - Aidinis, Vassilis

AU - Kane, Daniel A.

AU - Pulinilkunnil, Thomas

AU - Kienesberger, Petra C.

PY - 2018

Y1 - 2018

KW - Diet effects/lipid metabolism

KW - Glucose

KW - Pyruvate

KW - Respiration

KW - Skeletal muscle

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DO - 10.1194/jlr.M082008

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SN - 0022-2275

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JO - Journal of Lipid Research

JF - Journal of Lipid Research

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ER -

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

ASJC Scopus Subject Areas

Keywords

UN SDGs

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