Autophagic homeostasis is required for the pluripotency of cancer stem cells

Keyphrases

• ATG12 10%
• ATG7 10%
• Autophagic 100%
• Autophagy 40%
• Autophagy Machinery 10%
• Basal Level 20%
• Brachyury 10%
• Cancer Stem Cells 100%
• Casein 10%
• Caudal Type Homeobox 2 10%
• CDX2 10%
• Cellular Pathways 10%
• Chemoresistance 10%
• Complex Interactions 10%
• CSN2 10%
• Differentiation Markers 10%
• Energy Metabolism 10%
• GATA Binding Protein 6 10%
• GATA6 10%
• Homeobox 10%
• Homeostasis 100%
• Human Cancer 10%
• Human Model 10%
• Knockdown 50%
• Murine Model 10%
• NAD+ Metabolism 10%
• NAD+ Synthesis 10%
• Nanog 20%
• Nicotinamide Phosphoribosyltransferase (NAMPT) 40%
• Novel Regulator 10%
• Octamer-binding Transcription Factor 4 (OCT4) 10%
• Pathophysiological Conditions 10%
• Pharmacological Inhibitors 10%
• Pluripotency 100%
• Pluripotency Markers 10%
• POU Class 5 Homeobox 1 10%
• POU5F1 60%
• Rapamycin 10%
• Rate-limiting Enzyme 10%
• Regulating Effect 10%
• Secreted Phosphoprotein 1 (SPP1) 10%
• Self-renewal 10%
• Senescence 10%
• Serum Starvation 10%
• Stem Cell Factor 10%
• Stem Cell Pluripotency 10%
• Tat-Beclin 1 10%
• Transcription Factor 20%
• TUBB3 10%
• Tubulin 10%

Biochemistry, Genetics and Molecular Biology

• Casein 10%