Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

Azmeraw T. Amare; Anbupalam Thalamuthu; Klaus Oliver Schubert; Janice M. Fullerton; Muktar Ahmed; Simon Hartmann; Sergi Papiol; Urs Heilbronner; Franziska Degenhardt; Fasil Tekola-Ayele; Liping Hou; Yi Hsiang Hsu; Tatyana Shekhtman; Mazda Adli; Nirmala Akula; Kazufumi Akiyama; Raffaella Ardau; Bárbara Arias; Jean Michel Aubry; Roland Hasler; Hélène Richard-Lepouriel; Nader Perroud; Lena Backlund; Abesh Kumar Bhattacharjee; Frank Bellivier; Antonio Benabarre; Susanne Bengesser; Joanna M. Biernacka; Armin Birner; Cynthia Marie-Claire; Pablo Cervantes; Hsi Chung Chen; Caterina Chillotti; Sven Cichon; Cristiana Cruceanu; Piotr M. Czerski; Nina Dalkner; Maria Del Zompo; J. Raymond DePaulo; Bruno Étain; Stephane Jamain; Peter Falkai; Andreas J. Forstner; Louise Frisen; Mark A. Frye; Sébastien Gard; Julie S. Garnham; Fernando S. Goes; Maria Grigoroiu-Serbanescu; Andreas J. Fallgatter; Sophia Stegmaier; Thomas Ethofer; Silvia Biere; Kristiyana Petrova; Ceylan Schuster; Kristina Adorjan; Monika Budde; Maria Heilbronner; Janos L. Kalman; Mojtaba Oraki Kohshour; Daniela Reich-Erkelenz; Sabrina K. Schaupp; Eva C. Schulte; Fanny Senner; Thomas Vogl; Ion George Anghelescu; Volker Arolt; Udo Dannlowski; Detlef Dietrich; Christian Figge; Markus Jäger; Fabian U. Lang; Georg Juckel; Carsten Konrad; Jens Reimer; Max Schmauß; Andrea Schmitt; Carsten Spitzer; Martin von Hagen; Jens Wiltfang; Jörg Zimmermann; Till F.M. Andlauer; Andre Fischer; Felix Bermpohl; Philipp Ritter; Silke Matura; Anna Gryaznova; Irina Falkenberg; Cüneyt Yildiz; Tilo Kircher; Julia Schmidt; Marius Koch; Kathrin Gade; Sarah Trost; Ida S. Haussleiter; Martin Lambert; Anja C. Rohenkohl; Vivien Kraft; Paul Grof; Ryota Hashimoto; Joanna Hauser; Stefan Herms; Per Hoffmann; Esther Jiménez; Jean Pierre Kahn; Layla Kassem; Po Hsiu Kuo; Tadafumi Kato; John Kelsoe; Sarah Kittel-Schneider; Ewa Ferensztajn-Rochowiak; Barbara König; Ichiro Kusumi; Gonzalo Laje; Mikael Landén; Catharina Lavebratt; Marion Leboyer; Susan G. Leckband; Alfonso Tortorella; Mirko Manchia; Lina Martinsson; Michael J. McCarthy; Susan McElroy; Francesc Colom; Vincent Millischer; Marina Mitjans; Francis M. Mondimore; Palmiero Monteleone; Caroline M. Nievergelt; Markus M. Nöthen; Tomas Novák; Claire O’Donovan; Norio Ozaki; Andrea Pfennig; Claudia Pisanu; James B. Potash; Andreas Reif; Eva Reininghaus; Guy A. Rouleau; Janusz K. Rybakowski; Martin Schalling; Peter R. Schofield; Barbara W. Schweizer; Giovanni Severino; Paul D. Shilling; Katzutaka Shimoda; Christian Simhandl; Claire M. Slaney; Alessio Squassina; Thomas Stamm; Pavla Stopkova; Mario Maj; Gustavo Turecki; Eduard Vieta; Julia Veeh; Stephanie H. Witt; Adam Wright; Peter P. Zandi; Philip B. Mitchell; Michael Bauer; Martin Alda; Marcella Rietschel; Francis J. McMahon; Thomas G. Schulze; Scott R. Clark; Bernhard T. Baune

doi:10.1038/s41380-023-02149-1

Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

Azmeraw T. Amare, Anbupalam Thalamuthu, Klaus Oliver Schubert, Janice M. Fullerton, Muktar Ahmed, Simon Hartmann, Sergi Papiol, Urs Heilbronner, Franziska Degenhardt, Fasil Tekola-Ayele, Liping Hou, Yi Hsiang Hsu, Tatyana Shekhtman, Mazda Adli, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, Bárbara Arias, Jean Michel Aubry, Roland HaslerHélène Richard-Lepouriel, Nader Perroud, Lena Backlund, Abesh Kumar Bhattacharjee, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Joanna M. Biernacka, Armin Birner, Cynthia Marie-Claire, Pablo Cervantes, Hsi Chung Chen, Caterina Chillotti, Sven Cichon, Cristiana Cruceanu, Piotr M. Czerski, Nina Dalkner, Maria Del Zompo, J. Raymond DePaulo, Bruno Étain, Stephane Jamain, Peter Falkai, Andreas J. Forstner, Louise Frisen, Mark A. Frye, Sébastien Gard, Julie S. Garnham, Fernando S. Goes, Maria Grigoroiu-Serbanescu, Andreas J. Fallgatter, Sophia Stegmaier, Thomas Ethofer, Silvia Biere, Kristiyana Petrova, Ceylan Schuster, Kristina Adorjan, Monika Budde, Maria Heilbronner, Janos L. Kalman, Mojtaba Oraki Kohshour, Daniela Reich-Erkelenz, Sabrina K. Schaupp, Eva C. Schulte, Fanny Senner, Thomas Vogl, Ion George Anghelescu, Volker Arolt, Udo Dannlowski, Detlef Dietrich, Christian Figge, Markus Jäger, Fabian U. Lang, Georg Juckel, Carsten Konrad, Jens Reimer, Max Schmauß, Andrea Schmitt, Carsten Spitzer, Martin von Hagen, Jens Wiltfang, Jörg Zimmermann, Till F.M. Andlauer, Andre Fischer, Felix Bermpohl, Philipp Ritter, Silke Matura, Anna Gryaznova, Irina Falkenberg, Cüneyt Yildiz, Tilo Kircher, Julia Schmidt, Marius Koch, Kathrin Gade, Sarah Trost, Ida S. Haussleiter, Martin Lambert, Anja C. Rohenkohl, Vivien Kraft, Paul Grof, Ryota Hashimoto, Joanna Hauser, Stefan Herms, Per Hoffmann, Esther Jiménez, Jean Pierre Kahn, Layla Kassem, Po Hsiu Kuo, Tadafumi Kato, John Kelsoe, Sarah Kittel-Schneider, Ewa Ferensztajn-Rochowiak, Barbara König, Ichiro Kusumi, Gonzalo Laje, Mikael Landén, Catharina Lavebratt, Marion Leboyer, Susan G. Leckband, Alfonso Tortorella, Mirko Manchia, Lina Martinsson, Michael J. McCarthy, Susan McElroy, Francesc Colom, Vincent Millischer, Marina Mitjans, Francis M. Mondimore, Palmiero Monteleone, Caroline M. Nievergelt, Markus M. Nöthen, Tomas Novák, Claire O’Donovan, Norio Ozaki, Andrea Pfennig, Claudia Pisanu, James B. Potash, Andreas Reif, Eva Reininghaus, Guy A. Rouleau, Janusz K. Rybakowski, Martin Schalling, Peter R. Schofield, Barbara W. Schweizer, Giovanni Severino, Paul D. Shilling, Katzutaka Shimoda, Christian Simhandl, Claire M. Slaney, Alessio Squassina, Thomas Stamm, Pavla Stopkova, Mario Maj, Gustavo Turecki, Eduard Vieta, Julia Veeh, Stephanie H. Witt, Adam Wright, Peter P. Zandi, Philip B. Mitchell, Michael Bauer, Martin Alda, Marcella Rietschel, Francis J. McMahon, Thomas G. Schulze, Scott R. Clark, Bernhard T. Baune

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Original language	English
Journal	Molecular Psychiatry
DOIs	https://doi.org/10.1038/s41380-023-02149-1
Publication status	Accepted/In press - 2023
Externally published	Yes

ASJC Scopus Subject Areas

Molecular Biology
Cellular and Molecular Neuroscience
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/s41380-023-02149-1

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Amare, A. T., Thalamuthu, A., Schubert, K. O., Fullerton, J. M., Ahmed, M., Hartmann, S., Papiol, S., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hou, L., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., ... Baune, B. T. (Accepted/In press). Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder. Molecular Psychiatry. https://doi.org/10.1038/s41380-023-02149-1

Amare, AT, Thalamuthu, A, Schubert, KO, Fullerton, JM, Ahmed, M, Hartmann, S, Papiol, S, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hou, L, Hsu, YH, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, JM, Hasler, R, Richard-Lepouriel, H, Perroud, N, Backlund, L, Bhattacharjee, AK, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, JM, Birner, A, Marie-Claire, C, Cervantes, P, Chen, HC, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, PM, Dalkner, N, Del Zompo, M, DePaulo, JR, Étain, B, Jamain, S, Falkai, P, Forstner, AJ, Frisen, L, Frye, MA, Gard, S, Garnham, JS, Goes, FS, Grigoroiu-Serbanescu, M, Fallgatter, AJ, Stegmaier, S, Ethofer, T, Biere, S, Petrova, K, Schuster, C, Adorjan, K, Budde, M, Heilbronner, M, Kalman, JL, Kohshour, MO, Reich-Erkelenz, D, Schaupp, SK, Schulte, EC, Senner, F, Vogl, T, Anghelescu, IG, Arolt, V, Dannlowski, U, Dietrich, D, Figge, C, Jäger, M, Lang, FU, Juckel, G, Konrad, C, Reimer, J, Schmauß, M, Schmitt, A, Spitzer, C, von Hagen, M, Wiltfang, J, Zimmermann, J, Andlauer, TFM, Fischer, A, Bermpohl, F, Ritter, P, Matura, S, Gryaznova, A, Falkenberg, I, Yildiz, C, Kircher, T, Schmidt, J, Koch, M, Gade, K, Trost, S, Haussleiter, IS, Lambert, M, Rohenkohl, AC, Kraft, V, Grof, P, Hashimoto, R, Hauser, J, Herms, S, Hoffmann, P, Jiménez, E, Kahn, JP, Kassem, L, Kuo, PH, Kato, T, Kelsoe, J, Kittel-Schneider, S, Ferensztajn-Rochowiak, E, König, B, Kusumi, I, Laje, G, Landén, M, Lavebratt, C, Leboyer, M, Leckband, SG, Tortorella, A, Manchia, M, Martinsson, L, McCarthy, MJ, McElroy, S, Colom, F, Millischer, V, Mitjans, M, Mondimore, FM, Monteleone, P, Nievergelt, CM, Nöthen, MM, Novák, T, O’Donovan, C, Ozaki, N, Pfennig, A, Pisanu, C, Potash, JB, Reif, A, Reininghaus, E, Rouleau, GA, Rybakowski, JK, Schalling, M, Schofield, PR, Schweizer, BW, Severino, G, Shilling, PD, Shimoda, K, Simhandl, C, Slaney, CM, Squassina, A, Stamm, T, Stopkova, P, Maj, M, Turecki, G, Vieta, E, Veeh, J, Witt, SH, Wright, A, Zandi, PP, Mitchell, PB, Bauer, M, Alda, M, Rietschel, M, McMahon, FJ, Schulze, TG, Clark, SR & Baune, BT 2023, 'Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder', Molecular Psychiatry. https://doi.org/10.1038/s41380-023-02149-1

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year = "2023",

doi = "10.1038/s41380-023-02149-1",

language = "English",

journal = "Molecular Psychiatry",

issn = "1359-4184",

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TY - JOUR

T1 - Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

AU - Amare, Azmeraw T.

AU - Thalamuthu, Anbupalam

AU - Schubert, Klaus Oliver

AU - Fullerton, Janice M.

AU - Ahmed, Muktar

AU - Hartmann, Simon

AU - Papiol, Sergi

AU - Heilbronner, Urs

AU - Degenhardt, Franziska

AU - Tekola-Ayele, Fasil

AU - Hou, Liping

AU - Hsu, Yi Hsiang

AU - Shekhtman, Tatyana

AU - Adli, Mazda

AU - Akula, Nirmala

AU - Akiyama, Kazufumi

AU - Ardau, Raffaella

AU - Arias, Bárbara

AU - Aubry, Jean Michel

AU - Hasler, Roland

AU - Richard-Lepouriel, Hélène

AU - Perroud, Nader

AU - Backlund, Lena

AU - Bhattacharjee, Abesh Kumar

AU - Bellivier, Frank

AU - Benabarre, Antonio

AU - Bengesser, Susanne

AU - Biernacka, Joanna M.

AU - Birner, Armin

AU - Marie-Claire, Cynthia

AU - Cervantes, Pablo

AU - Chen, Hsi Chung

AU - Chillotti, Caterina

AU - Cichon, Sven

AU - Cruceanu, Cristiana

AU - Czerski, Piotr M.

AU - Dalkner, Nina

AU - Del Zompo, Maria

AU - DePaulo, J. Raymond

AU - Étain, Bruno

AU - Jamain, Stephane

AU - Falkai, Peter

AU - Forstner, Andreas J.

AU - Frisen, Louise

AU - Frye, Mark A.

AU - Gard, Sébastien

AU - Garnham, Julie S.

AU - Goes, Fernando S.

AU - Grigoroiu-Serbanescu, Maria

AU - Fallgatter, Andreas J.

AU - Stegmaier, Sophia

AU - Ethofer, Thomas

AU - Biere, Silvia

AU - Petrova, Kristiyana

AU - Schuster, Ceylan

AU - Adorjan, Kristina

AU - Budde, Monika

AU - Heilbronner, Maria

AU - Kalman, Janos L.

AU - Kohshour, Mojtaba Oraki

AU - Reich-Erkelenz, Daniela

AU - Schaupp, Sabrina K.

AU - Schulte, Eva C.

AU - Senner, Fanny

AU - Vogl, Thomas

AU - Anghelescu, Ion George

AU - Arolt, Volker

AU - Dannlowski, Udo

AU - Dietrich, Detlef

AU - Figge, Christian

AU - Jäger, Markus

AU - Lang, Fabian U.

AU - Juckel, Georg

AU - Konrad, Carsten

AU - Reimer, Jens

AU - Schmauß, Max

AU - Schmitt, Andrea

AU - Spitzer, Carsten

AU - von Hagen, Martin

AU - Wiltfang, Jens

AU - Zimmermann, Jörg

AU - Andlauer, Till F.M.

AU - Fischer, Andre

AU - Bermpohl, Felix

AU - Ritter, Philipp

AU - Matura, Silke

AU - Gryaznova, Anna

AU - Falkenberg, Irina

AU - Yildiz, Cüneyt

AU - Kircher, Tilo

AU - Schmidt, Julia

AU - Koch, Marius

AU - Gade, Kathrin

AU - Trost, Sarah

AU - Haussleiter, Ida S.

AU - Lambert, Martin

AU - Rohenkohl, Anja C.

AU - Kraft, Vivien

AU - Grof, Paul

AU - Hashimoto, Ryota

AU - Hauser, Joanna

AU - Herms, Stefan

AU - Hoffmann, Per

AU - Jiménez, Esther

AU - Kahn, Jean Pierre

AU - Kassem, Layla

AU - Kuo, Po Hsiu

AU - Kato, Tadafumi

AU - Kelsoe, John

AU - Kittel-Schneider, Sarah

AU - Ferensztajn-Rochowiak, Ewa

AU - König, Barbara

AU - Kusumi, Ichiro

AU - Laje, Gonzalo

AU - Landén, Mikael

AU - Lavebratt, Catharina

AU - Leboyer, Marion

AU - Leckband, Susan G.

AU - Tortorella, Alfonso

AU - Manchia, Mirko

AU - Martinsson, Lina

AU - McCarthy, Michael J.

AU - McElroy, Susan

AU - Colom, Francesc

AU - Millischer, Vincent

AU - Mitjans, Marina

AU - Mondimore, Francis M.

AU - Monteleone, Palmiero

AU - Nievergelt, Caroline M.

AU - Nöthen, Markus M.

AU - Novák, Tomas

AU - O’Donovan, Claire

AU - Ozaki, Norio

AU - Pfennig, Andrea

AU - Pisanu, Claudia

AU - Potash, James B.

AU - Reif, Andreas

AU - Reininghaus, Eva

AU - Rouleau, Guy A.

AU - Rybakowski, Janusz K.

AU - Schalling, Martin

AU - Schofield, Peter R.

AU - Schweizer, Barbara W.

AU - Severino, Giovanni

AU - Shilling, Paul D.

AU - Shimoda, Katzutaka

AU - Simhandl, Christian

AU - Slaney, Claire M.

AU - Squassina, Alessio

AU - Stamm, Thomas

AU - Stopkova, Pavla

AU - Maj, Mario

AU - Turecki, Gustavo

AU - Vieta, Eduard

AU - Veeh, Julia

AU - Witt, Stephanie H.

AU - Wright, Adam

AU - Zandi, Peter P.

AU - Mitchell, Philip B.

AU - Bauer, Michael

AU - Alda, Martin

AU - Rietschel, Marcella

AU - McMahon, Francis J.

AU - Schulze, Thomas G.

AU - Clark, Scott R.

AU - Baune, Bernhard T.

PY - 2023

Y1 - 2023

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UR - http://www.scopus.com/inward/citedby.url?scp=85164527779&partnerID=8YFLogxK

U2 - 10.1038/s41380-023-02149-1

DO - 10.1038/s41380-023-02149-1

M3 - Article

C2 - 37433967

AN - SCOPUS:85164527779

SN - 1359-4184

JO - Molecular Psychiatry

JF - Molecular Psychiatry

ER -

Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

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UN SDGs

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