Altering the Y137-K164-K166 triad of mandelate racemase and its effect on the observed pKa of the Brønsted base catalysts

Christopher M. Fetter, Zachary A. Morrison, Mitesh Nagar, Colin D. Douglas, Stephen L. Bearne

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)
Original languageEnglish
Pages (from-to)116-126
Number of pages11
JournalArchives of Biochemistry and Biophysics
Volume666
DOIs
Publication statusPublished - May 15 2019

ASJC Scopus Subject Areas

  • Molecular Biology
  • Biophysics
  • Biochemistry

Keywords

  • Enolase superfamily
  • Inhibition
  • Mandelate racemase
  • Site-directed mutagenesis
  • pH-rate profiles
  • pK perturbation

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