A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

Heshan Peiris; Michael D. Duffield; Joao Fadista; Claire F. Jessup; Vinder Kashmir; Amanda J. Genders; Sean L. McGee; Alyce M. Martin; Madiha Saiedi; Nicholas Morton; Roderick Carter; Michael A. Cousin; Alexandros C. Kokotos; Nikolay Oskolkov; Petr Volkov; Tertius A. Hough; Elizabeth M.C. Fisher; Victor L.J. Tybulewicz; Jorge Busciglio; Pinar E. Coskun; Ann Becker; Pavel V. Belichenko; William C. Mobley; Michael T. Ryan; Jeng Yie Chan; D. Ross Laybutt; P. Toby Coates; Sijun Yang; Charlotte Ling; Leif Groop; Melanie A. Pritchard; Damien J. Keating

doi:10.1371/journal.pgen.1006033

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

Heshan Peiris, Michael D. Duffield, Joao Fadista, Claire F. Jessup, Vinder Kashmir, Amanda J. Genders, Sean L. McGee, Alyce M. Martin, Madiha Saiedi, Nicholas Morton, Roderick Carter, Michael A. Cousin, Alexandros C. Kokotos, Nikolay Oskolkov, Petr Volkov, Tertius A. Hough, Elizabeth M.C. Fisher, Victor L.J. Tybulewicz, Jorge Busciglio, Pinar E. CoskunAnn Becker, Pavel V. Belichenko, William C. Mobley, Michael T. Ryan, Jeng Yie Chan, D. Ross Laybutt, P. Toby Coates, Sijun Yang, Charlotte Ling, Leif Groop, Melanie A. Pritchard, Damien J. Keating

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Original language	English
Article number	e1006033
Journal	PLoS Genetics
Volume	12
Issue number	5
DOIs	https://doi.org/10.1371/journal.pgen.1006033
Publication status	Published - May 2016
Externally published	Yes

ASJC Scopus Subject Areas

Ecology, Evolution, Behavior and Systematics
Molecular Biology
Genetics
Genetics(clinical)
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1371/journal.pgen.1006033

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Peiris, H., Duffield, M. D., Fadista, J., Jessup, C. F., Kashmir, V., Genders, A. J., McGee, S. L., Martin, A. M., Saiedi, M., Morton, N., Carter, R., Cousin, M. A., Kokotos, A. C., Oskolkov, N., Volkov, P., Hough, T. A., Fisher, E. M. C., Tybulewicz, V. L. J., Busciglio, J., ... Keating, D. J. (2016). A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes. PLoS Genetics, 12(5), Article e1006033. https://doi.org/10.1371/journal.pgen.1006033

Peiris, H, Duffield, MD, Fadista, J, Jessup, CF, Kashmir, V, Genders, AJ, McGee, SL, Martin, AM, Saiedi, M, Morton, N, Carter, R, Cousin, MA, Kokotos, AC, Oskolkov, N, Volkov, P, Hough, TA, Fisher, EMC, Tybulewicz, VLJ, Busciglio, J, Coskun, PE, Becker, A, Belichenko, PV, Mobley, WC, Ryan, MT, Chan, JY, Laybutt, DR, Coates, PT, Yang, S, Ling, C, Groop, L, Pritchard, MA & Keating, DJ 2016, 'A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes', PLoS Genetics, vol. 12, no. 5, e1006033. https://doi.org/10.1371/journal.pgen.1006033

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AU - Peiris, Heshan

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AU - Jessup, Claire F.

AU - Kashmir, Vinder

AU - Genders, Amanda J.

AU - McGee, Sean L.

AU - Martin, Alyce M.

AU - Saiedi, Madiha

AU - Morton, Nicholas

AU - Carter, Roderick

AU - Cousin, Michael A.

AU - Kokotos, Alexandros C.

AU - Oskolkov, Nikolay

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AU - Fisher, Elizabeth M.C.

AU - Tybulewicz, Victor L.J.

AU - Busciglio, Jorge

AU - Coskun, Pinar E.

AU - Becker, Ann

AU - Belichenko, Pavel V.

AU - Mobley, William C.

AU - Ryan, Michael T.

AU - Chan, Jeng Yie

AU - Laybutt, D. Ross

AU - Coates, P. Toby

AU - Yang, Sijun

AU - Ling, Charlotte

AU - Groop, Leif

AU - Pritchard, Melanie A.

AU - Keating, Damien J.

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A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

ASJC Scopus Subject Areas

UN SDGs

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