@article{47bff1aa23a9451cb39c1d5d33045885,
title = "A risk-based approach to experimental early phase clinical trials during the COVID-19 pandemic",
author = "Crescens Tiu and Rajiv Shinde and Christina Yap and {Rao Baikady}, Bindumalini and Udai Banerji and Minchom, {Anna R.} and {de Bono}, {Johann S.} and Lopez, {Juanita S.}",
note = "Funding Information: The authors acknowledge infrastructural support from Cancer Research UK, The Experimental Cancer Medicine Centre, and Biomedical Research Centre Initiatives awarded to The Institute of Cancer Research and The Royal Marsden Hospital National Health Service Foundation Trust. UB is a recipient of an NIHR Research Professorship Award. CY reports personal fees from Celgene and Faron Pharmaceuticals, outside the submitted work. UB reports grants from Onyx Pharmaceuticals/BTG International and AstraZeneca; personal fees from Eli Lilly, Phoenix ACT, Karus Therapeutics, Novartis, Astellas, Janssen, Boehringer-Ingelheim; and other support from Bayer, all outside the submitted work. ARM reports personal fees from Janssen Pharmaceuticals, Faron Pharmaceuticals, Bayer Pharmaceuticals, Novartis Oncology, and Merck Pharmaceuticals; and other support from LOXO Oncology, all outside the submitted work. JSdB reports personal fees and non-financial support from Astellas Pharma and Sanofi; grants, personal fees, and non-financial support from AstraZeneca; personal fees from Genentech/Roche, Pfizer, Bayer, Boehringer Ingelheim, Merck Serono, Merck Sharp & Dohme, and Janssen; non-financial support from Genmab, Orion Pharma GmbH, Qiagen, Taiho Pharmaceutical, and Vertex; and personal fees and other support from Cellcentric, Daiichi, GlaxoSmithKlein, Menarini/Silicon Biosystems, and Sierra Oncology, all outside the submitted work. In addition, JSdB has a patent on 17-substituted steroids useful in cancer treatment with royalties paid to Janssen, and a patent on PARP inhibitors and DNA repair defects with royalties paid to AstraZeneca. CT, RS, and BRB declare no competing interests.",
year = "2020",
month = jul,
doi = "10.1016/S1470-2045(20)30339-9",
language = "English",
volume = "21",
pages = "889--891",
journal = "The Lancet Oncology",
issn = "1470-2045",
publisher = "Lancet Publishing Group",
number = "7",
}