A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

Keyphrases

• Disease Status 16%
• DNA Variants 16%
• Genetic Architecture 33%
• Genetic Risk 16%
• Genome-wide Association Study 16%
• Independent Tuning 16%
• Lassosum 16%
• LDpred 16%
• Left out 16%
• Major Depressive Disorder 50%
• Meta-analysis 16%
• Multiple Cohorts 100%
• Number of Factors 16%
• Phenotype Definition 16%
• Polygenic Score 100%
• Prediction Statistics 16%
• PRS-CS 33%
• Psychiatric Disorders 100%
• Psychiatric Genomics Consortium 16%
• Repeated Application 16%
• Risk Allele 16%
• Schizophrenia 50%
• Score Method 100%
• T-method 16%
• Technical Factors 16%

Neuroscience

• Dementia Praecox 100%
• Genome-Wide Association Study 33%
• Major Depressive Disorder 100%
• Meta-Analysis 33%

Biochemistry, Genetics and Molecular Biology

• Allele 50%
• Genetic Architecture 100%
• Genetic Risk 50%
• Genome-Wide Association Study 50%