A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo

Junjie Chen; Richard Peters; Partha Saha; Patrick Lee; Annie Theodoras; Michele Pagano; Gerhard Wagner; Anindya Dutta

doi:10.1093/nar/24.9.1727

A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo

Junjie Chen, Richard Peters, Partha Saha, Patrick Lee, Annie Theodoras, Michele Pagano, Gerhard Wagner, Anindya Dutta

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1727-1733
Number of pages	7
Journal	Nucleic Acids Research
Volume	24
Issue number	9
DOIs	https://doi.org/10.1093/nar/24.9.1727
Publication status	Published - 1996
Externally published	Yes

ASJC Scopus Subject Areas

Genetics

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@article{a84b9ab335904f90aea7f845812bddd9,

title = "A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo",

author = "Junjie Chen and Richard Peters and Partha Saha and Patrick Lee and Annie Theodoras and Michele Pagano and Gerhard Wagner and Anindya Dutta",

note = "Funding Information: We thank members of the Dutta Laboratory and G.Lindenmeyer and D.Gilbert for helpful discussions, J.Morrow for technical assistance, J.Parvin for reading the manuscript, C.Dahl for help with peptide synthesis and J.Lee for use of the CD spectrometer. This work was supported by a grant from the NIH (CA60499) and career development awards from the American Cancer Society (JFRA 474) and the US Armed Forces Medical Research Command (DAMD17-94-J-4064). JC was supported by a post-doctoral fellowship (DAMD 17-94-J-4070), RP is a Howard Hughes Medical Institute Physician Post-doctoral Fellow, and MP was supported in part by HSFP grant RG-496/93.",

year = "1996",

doi = "10.1093/nar/24.9.1727",

language = "English",

volume = "24",

pages = "1727--1733",

journal = "Nucleic Acids Research",

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publisher = "Oxford University Press",

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}

TY - JOUR

T1 - A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo

AU - Chen, Junjie

AU - Peters, Richard

AU - Saha, Partha

AU - Lee, Patrick

AU - Theodoras, Annie

AU - Pagano, Michele

AU - Wagner, Gerhard

AU - Dutta, Anindya

N1 - Funding Information: We thank members of the Dutta Laboratory and G.Lindenmeyer and D.Gilbert for helpful discussions, J.Morrow for technical assistance, J.Parvin for reading the manuscript, C.Dahl for help with peptide synthesis and J.Lee for use of the CD spectrometer. This work was supported by a grant from the NIH (CA60499) and career development awards from the American Cancer Society (JFRA 474) and the US Armed Forces Medical Research Command (DAMD17-94-J-4064). JC was supported by a post-doctoral fellowship (DAMD 17-94-J-4070), RP is a Howard Hughes Medical Institute Physician Post-doctoral Fellow, and MP was supported in part by HSFP grant RG-496/93.

PY - 1996

Y1 - 1996

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U2 - 10.1093/nar/24.9.1727

DO - 10.1093/nar/24.9.1727

M3 - Article

C2 - 8649992

AN - SCOPUS:0029873287

SN - 0305-1048

VL - 24

SP - 1727

EP - 1733

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - 9

ER -

A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo

ASJC Scopus Subject Areas

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